Can Piriformis syndrome cause muscles spasms and pain in the legs and buttocks?
You need to see an ortopedist
I have read your question and I understand your concern.
The knife-like pain you describe and the upper posterior thigh muscle spasm are very likely to be from piriformis syndrome. The problem with your menisci is chronic and in your age I doubt that the specialist will recommend any surgical intervention.
First of all you need to loose weight, if you are overweight, because this can only exacerbate your knee pain.
You also need to drink a lot of fluids, eat fruits and vegetables, because very often muscle spasms and cramps come from electrolyte imbalance.
Regarding to the medicine you take, Tinazidine 2mg is a drug that should be taken 3 times a day. It helps with muscle spasm.
I would not recommend Advil, since a chronic treatment with NSAIDs can cause stomach ulcer and clotting problems. Tylenol is a better approach, but it often is not as effective and does not yield the desired effect, pain relief.
I strongly recommend you to see an ortopedist. This specialist will not how to deal specifically with the piriformis syndrome and the menisci problem. There may be also a change with Tizanidine class or he/she may add some other drug.
I hope I have been helpful.
If you have any other question, please feel free to write.
Wish you good health!
Manoku Eni M.D.
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