Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

188 Doctors Online
Doctor Image
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

What causes leg edema while on Prednisone?

Answered by
Dr.
Dr. Salah Saad Shoman

Internal Medicine Specialist

Practicing since :2004

Answered : 1664 Questions

default
Posted on Fri, 11 May 2018 in Elderly Problems
Question: My blood vessels are very small in caliber size - one M.D. over 30 years ago stated it may have to be related to my use of 0ne year daily use of 20mg. of prednisone use. I,m age 77 years. this month.
My locate M.D. - generalist provided my medication because about every 5-6 months I have edema in my lower legs - both legs. He cannot understand the cause of my leg edema - heart, lungs, kidney's, other test are in range for my age.
I have had a short-gut ileostomy for over 43 years - do to IBD. Do you have any ideas on edema cause? I am a R.N. with a M.S. degree. - Thank you for your time.
doctor
Answered by Dr. Salah Saad Shoman 3 hours later
Brief Answer:
Prednisone side effects

Detailed Answer:
Dear sir, I have gone through your question and I understand your concerns . Prednisone can cause leg edema by several mechanisms which are :
1) sodium retention with the resulting edema , but in this case edema should be more generalized than confined to the lower limbs
2) venous insufficiency which occur due to incompetence of the venous valves.. In this case the edema gets worse with prolonged standing and gets better by raising the legs.. it might be accompanied by leg pain , sense of heaviness , itching , varicose viens, cramping or change of skin color..
3) hypothyroidism which can be a side effect of prolonged use of prednisone and can cause myxedema . this can be accompanied with edema of other parts of the body..
I would recommend that you take a blood test for thyroid hormonal profile including T3, T4 and TSH together with wearing a compression stockings and elevation of your legs with a pillow at night during sleep. I hope you find this helpful
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
premium_optimized

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions ,   ,  
Drug/Medication
Medical Procedures
Lab Tests

Recent questions on  Venous insufficiency

doctor1 MD

My son is 25 years old and is a smoker. He has had now two episodes that his feet swell and it appears he has also fluid retention on his feet and after approximately 24 hours the swelling dissapates. He is less active too.

doctor1 MD

Hi. I went on a cruise from Nov 27 to Dec 2 to Lebadee Haiti and Falmouth Jamaica. Since I got back I haven’t been feeling well. I have aches all over, tired, I feel feverish, and the strangest is a burning sensation in my left leg. It started in...

doctor1 MD

Hello. About two months ago I began having swelling in my feet and ankles, but mostly in my left foot/ankle. No pain, no discoloration, can walk/run just fine. It appeared to do this during the time of my menstrual cycle, and would come and go. This last month, the swelling remained. I went to my gyn who said it was bloating and gave me diuretics. It did not help. I then went to my internist who suggested thyroid issues (I do have a very tiny cyst on my thyroid that my doc has watched for the past two years) and venous insufficiency/reflux. My blood test to check thyroid was borderline normal, and I must retest next week. Also, my potassium levels are excellent, and my doctor does not suspect heart, kidney or liver problems. I had a Doppler ultrasound on both legs done last week, and the results were no venous reflux suspected/good circulation and no dvt. I am now being told to wear compression stockings to help with swelling. My only health issues are being overweight, poly cystic ovarian syndrome, large fibroids, large uterus, and severe cramping during menstruation. I take metformin prescribed by an endocrinologist to treat the pcos but I am not diabetic and my glucose levels are excellent. The swelling is in the ankles, foot and just above the ankle. The measurements of my legs (calf and thigh) are the same. The ankles measure 9 inches/right and 10 inches/left. I would like a second opinion. What other things could be causing the swelling in the left foot/ankle and occasional sharp pain in the calf at rest?

doctor1 MD

I have venous insufficiency in the left leg, I have had the RF about 10 years ago, and recently had the greater Staphenous vein removed. I have been in the hospital 3x for infection and have had vancomyicyn each time for extended periods of time. I currently take 8-200mg Motrin daily, 2-800mg Motrin and 4-500mg Tylenol pm at night so I can sleep. nothing seems to work, I cant get rid of the pain and cellulitis keeps reoccurring. The pain that I have had has been with me for at least 10 years and it has changed my outlook on life, my 8 year old son keeps me living. I will be 50 this year, I am overweight but trying to drop weight without much success, but I keep trying. I am always amazed when I wake up in the morning. any suggestions for the pain? Cardiovascular says to ask genral. genral says ask cardiovascular, I say forget it and keep uping the otc drugs

doctor1 MD

Hello Doctor, I m 63 old woman trying to lose weight ht:5 0.75 223 lbs I have several health issues: CAD of LAD @ 35 percent in 11/2009-no stents or heart attacks since that diagnosis. I have Nitrostat 0.4 mg tablet if needed for angina. Luckily, I have only needed this @ 3x At times in the past 2-3 years. I have available orally disasolvable soft tablet of klonopin for immediate relief of any chest pain etc., and if that don t work I will take my nitroglyserin if my BP is greater than 145-190 mmhg AND if my heart rate is greater than 100 beats per minute, AND if my angina lasts more than 5 . I also have sinus bradycardia if I don t exercise at least 1.5 hrs on a recumbent bike everyday and/or if I take more than 20 mg celexa. Also, hypothyroid-taking @137 mcg levothyroxine. Also gastritis-40 mg pantoprazole in am, and 20 mg famotidine in pm. Also 1000 mg Ranexa for the heart, 20 mg atorvastin, and 10 mg Zetia. I have also been diagnosed with panic disorder with major depression-10 mg celexa and 0.125 mg klonopin in am, 5 mg celexa and 0.125 mg klonopin in pm. At midnight I take 150 mg Bupropion with my statin drugs. I Also take 1-325 mg in am and 81 mg aspirin in pm. Over the counter: 100 mg tocotrienols. 500 mg turmeric. Nutrilite Daily Free Vitamin. Glucosamine, Chondroitin, MSM. 90 mcg Vitamin K-2 & 6000 IU Vitamin D-3 1200 mg calcium carbonate 500 mg magnesium oxide. Cinnamon w/chromium @ 9 tablets daily Vitamin C-3000 mg and Pauline Therapy Essential Formula-with 3000 mg vitamin C and B vitamins, L-Proline, L-Lysine, L-Arginine and 6 mg lutein, 4 mg zeaxanthin. Other diseases: scoliosis, disc degeneration of the spine, sciatica, osteoarthritis of left knee, venous insufficiency, increased lipoprotein A of the blood, beginning nuclear cataracts in both eyes and floaters As you can see, I take a lot of different medications and supplements (by my own choice) I am interested in getting my weight down. I have lost @ 50 lbs since 2009. Since I have lost 0.75 in height in the past one or two years, I m really interested in getting my weight down to lessen the pressure on the vertebrae of the spine? I hope I haven t overwhelmed you with information--but is it SAFE to take the latest fat-reducing hyped supplement: Green Coffee Bean? Thanks Sandra Osowski