Brief Answer:
Needs work up and management,

Detailed Answer:
Thank you for asking XXXX!
Ativan / Lorazepam is a sedative hypnotic agent used in anxiety and panic disorders and insomnia and chemo induced nausea and vomiting and epilepsy.
Now you used it in recommended dose for years. and your body has got addicted to it and a single missed dose recurs with the adverse effects and withdrawal symptoms.
Now you using simultaneously of Amitriptyline/ elavil antidepressant, a TCA one which is no way a good option in insomnia and heart patients and is not recommended as they both potentiate the effect of each other and should not be used together.
Your history of carvedilol use and lipid lowering agents make it worth examination by a cardiologist too to sort out any cardiac involvement as leg pain and cold sweats may indicated cardiac perfusion issues.
I nut shell, avoid the medicines intake of ativan and elavil together, seek your psychiatrist and let him reshuffle the dosages for you and i suggest put you off of this TCA elavil as they themselves are insomniac and heart non friendly as they increase epinephrines by blocking their reuptake. Request them to put you on SSRIs for the depression. Seek a sleep disorder specialist for this insomnia.
But i would want you to pay a visit to a cardiologist oo to rule out any cardiac reason for these cold sweats and fatigue and leg pains as that might need some intervention and workup and management accordingly.
Hope it helps.Dont forget to close the discussion please.
May the odds be ever in your favour
Regards
S Khan

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