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Suggest Treatment For Constipation,pain In Abdomen And Pain In Rectum

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Posted on Mon, 16 Jun 2014
Question: Took 4 months and multiple rounds of Vancomyicin then 2 rounds of dificid resolve c diff. Now having idiopathic constipation, pain in abdomen pain in rectum 3 out of 4 days a week. Tried lizness l
ower dose but made me very weak and sick. Been dealing with this for 5 myths. When will I feel better and work again
YYYY@YYYY .
doctor
Answered by Dr. Shafi Ullah Khan (9 hours later)
Brief Answer:
Needs management, too early for Idiopathic

Detailed Answer:
Thank you for asking!
I am really sorry for your GI symptoms. Alternate bowel movements from diarrhoea of a colitis to a constipation not relieved by linaclotide is a likely cause of Inflammatory bowel and it needs work up and management.
I am sure you used lizness/ linaclotide at a recommended dose of 145 mcg PO once a day on empty stomach; at least 30 minutes before first meal of the day.
Lower gastrointestinal (GI) endoscopy, colonic transit study, defecography, anorectal manometry, surface anal electromyography (EMG), and balloon expulsion ,complete blood count (CBC),Thyroid function tests, Serum electrolytes for metabolic cause of constipation, such as hypokalemia and hypercalcemia and also potassium, calcium, glucose, and creatinine, for electrolytes imbalance and last but not the least histopathological examinations are some of the baseline workup necessary to sort out the constipation cause. Sometimes It is too early to cause a constipation an idiopathic one a a little digging deeper can come up with a clue.
Increase fiber intake and take plenty of fluids. manual disimpaction and transrectal enemas would work for a while now. Then a complete management would be needed and should focus on dietary change and exercise rather than laxatives, enemas, and suppositories, none of which really address the underlying problem.

The key to treating most patients with constipation is correction of dietary deficiencies, which generally involves increasing intake of fiber and fluid and decreasing the use of constipating agents (eg, milk products, coffee, tea, alcohol).

Medications to treat constipation include the following:

Bulk-forming agents (fibers; eg, psyllium): arguably the best and least expensive medication for long-term treatment
Emollient stool softeners (eg, docusate): Best used for short-term prophylaxis (eg, postoperative)
Rapidly acting lubricants (eg, mineral oil): Used for acute or subacute management of constipation
Prokinetics (eg, tegaserod): Proposed for use with severe constipation-predominant symptoms
Stimulant laxatives (eg, senna): Over-the-counter agents commonly but inappropriately used for long-term treatment of constipation
Newer therapies for constipation include the following:

Prucalopride, a prokinetic selective 5-hydroxytryptamine-4 (5-HT4) receptor antagonist that stimulates colonic motility and decreases transit time
The osmotic agents lubiprostone and linaclotide,which are FDA approved for chronic idiopathic constipation, constipation caused by irritable bowel syndrome, and (in the case of lubiprostone) opioid-induced constipation in adults with chronic, noncancer pain
Get to your gastroenterologist and discuss some newer advancements like sacral nerve stimulation and some surgical interventions if need be with them and let them decide what is best for you.
I hope it helps. Dont forget to close the discussion please.
Regards
S Khan
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Shafi Ullah Khan

General & Family Physician

Practicing since :2012

Answered : 3613 Questions

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Suggest Treatment For Constipation,pain In Abdomen And Pain In Rectum

Brief Answer: Needs management, too early for Idiopathic Detailed Answer: Thank you for asking! I am really sorry for your GI symptoms. Alternate bowel movements from diarrhoea of a colitis to a constipation not relieved by linaclotide is a likely cause of Inflammatory bowel and it needs work up and management. I am sure you used lizness/ linaclotide at a recommended dose of 145 mcg PO once a day on empty stomach; at least 30 minutes before first meal of the day. Lower gastrointestinal (GI) endoscopy, colonic transit study, defecography, anorectal manometry, surface anal electromyography (EMG), and balloon expulsion ,complete blood count (CBC),Thyroid function tests, Serum electrolytes for metabolic cause of constipation, such as hypokalemia and hypercalcemia and also potassium, calcium, glucose, and creatinine, for electrolytes imbalance and last but not the least histopathological examinations are some of the baseline workup necessary to sort out the constipation cause. Sometimes It is too early to cause a constipation an idiopathic one a a little digging deeper can come up with a clue. Increase fiber intake and take plenty of fluids. manual disimpaction and transrectal enemas would work for a while now. Then a complete management would be needed and should focus on dietary change and exercise rather than laxatives, enemas, and suppositories, none of which really address the underlying problem. The key to treating most patients with constipation is correction of dietary deficiencies, which generally involves increasing intake of fiber and fluid and decreasing the use of constipating agents (eg, milk products, coffee, tea, alcohol). Medications to treat constipation include the following: Bulk-forming agents (fibers; eg, psyllium): arguably the best and least expensive medication for long-term treatment Emollient stool softeners (eg, docusate): Best used for short-term prophylaxis (eg, postoperative) Rapidly acting lubricants (eg, mineral oil): Used for acute or subacute management of constipation Prokinetics (eg, tegaserod): Proposed for use with severe constipation-predominant symptoms Stimulant laxatives (eg, senna): Over-the-counter agents commonly but inappropriately used for long-term treatment of constipation Newer therapies for constipation include the following: Prucalopride, a prokinetic selective 5-hydroxytryptamine-4 (5-HT4) receptor antagonist that stimulates colonic motility and decreases transit time The osmotic agents lubiprostone and linaclotide,which are FDA approved for chronic idiopathic constipation, constipation caused by irritable bowel syndrome, and (in the case of lubiprostone) opioid-induced constipation in adults with chronic, noncancer pain Get to your gastroenterologist and discuss some newer advancements like sacral nerve stimulation and some surgical interventions if need be with them and let them decide what is best for you. I hope it helps. Dont forget to close the discussion please. Regards S Khan