Question: I recently was noted to have a 6mm gastric polyp with eosinophilic and extensive collagenous deposition on end. I had chronic gastritis at the general junction. Biopsies of the 2nd part of the duodenum showed eosinophilic. I have anorexia as well as alternating constipation and Streator XXXXXXX I prefer liquids. I've lost about 7 it's in 2 most. I also have widespread joint pain and 2 tests,one blood and one stool mildly positive for IBM. MOTHER has crohns. Not sure if allergy or I don't etiology most likely and what is recommended next strp.

Thanks for your prompt response.

I have had calfetoprotein level of 176 (ref 160). I had ASCA 1:70 although i was on steroids at the time of the test. I had a vitamin D level of 14. (I have checked in periodically and it has been as low as 6). I did 3 mos of high dose vitamin D, and probably need recheck. B12 was in the 500-600 range. Biotin was elevated, but I was taking a supplement because my hair was thinning. Colonoscopy was negative visually and as far as biopsies. My last CBC showed mild anemia 11.3. Previously, RBC count tends to be in the low normal range. (I have G6PD deficiency level 1.03 (ref 4.5)) My father has a very severe form of the disease.
I have been tested for lupus--neg, rheumatoid arthritis-neg, ankylosing spondylitis--HLA B27---neg.

I had either a severe allergic reaction or SJ reaction to Lamictal the day after thanksgiving in 2015. I had been on the medication x 2 months. I white oral plaques on my tongue, lips, buccal mucosa hard/soft palate and post. pharynx. These literally developed overnight. Pain level was 8/10. Voice was gone. Was in hospital with IV benadryl and steroids x 24 hrs. Sent home with nystatin and fluconazole, but symptoms worsened. (Prior to that I had perirectal symptoms of thrombosed hemorrhoid, anal tear, tenesmus, diarrhea, and what I though were hemorrhoids as well as unusual vaginal odor without discharge for a few weeks). Interestingly, these symptoms as well as the oral symptoms went away in about a week to 10 days on high dose steroids which I ended up taking for about 2 months.

Joint pain started after end of steroid treatment. Started in left thumb but quickly involved hands, wrists, elbows, sometimes rotator cuff and hips. Also spine (LS spine and SI joints particularly) and achilles insertion, base of 5th metatarsal and right 1st mtp joint and metatarsal heads. I am nearly always in some pain. I am on tramadol 50 mg TID currently or I would have trouble functioning daily.

I wonder if the steroid treatment may have muddied the water as it relates to IBD? Also, since tests for other types of arthritis are negative--and my ESR has been only as high as 11, what other etiology could cause such significant joint pain?
I am scheduled for capsule endoscopy and will call the allergist about additional testing.

I have arthritis in my right great toe. Have reviewed xrays 1 year apart and noted progression, however, I have never been in the level or the distribution of pain that I a currently experiencing. Although I am not a vegetarian, I do not eat a lot of meat, have no kidney stones, all UAs were normal so I doubt gout as an etiology. Also, although joints are painful they are not hot and red. Pain is in large as well as in small joints. Also, I have esthenopathy. This started in my left thumb, then right, fingers, and worked it's way down. Is this pattern characteristic and distribution typical of steroid induced arthralgia/arthritis. I have seen a rheumatologist and she keeps suspecting fibromyalgia although I have none of the classic tender points. I don't have muscle pain, only joint, ligament and tendon pain.


I tend to drink more than eat. Eating tends to cause upper abdominal and periumbilical pain. I have to have bm within an hour typically and often I have urgency symptoms and tenismus. Stools are generally hard OR soft/loose and floating. When I don't eat I tend to not have problems. I have yet to associate a particular food except pizza which seems to cause more problems than anything else. Is this then more consistent with IBS?