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My Uncle Has A Severe Deep Vein Thrombosis (DVT). It

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Posted on Sun, 5 May 2019
Question: My uncle has a severe deep vein thrombosis (DVT). It started in 1996, when he was 26 years old. He broke his leg, doctors applied cast, after remove of the case, the leg started to inflate (become bigger and bigger). During year of 1996, doctors said that inflation of the leg is normal and mention it will heal on its own. In 1997, he started experiencing ulcers on his calf it was small dot but now as you can see on the pictures it big. At the present time my uncle is 49 years old.
Right leg DVT/ulcer
His height is: 193 cm or 6”3
Weight: 142 kg or 313 pounds
The length of the ulcers wound is 2.7 inch by width 1.9 inches, depth of the wounds is approximately 1-2mm
-     Feeling fatigue/restless when he walks to much
-     Blood pressure is 130/80
-     Urine sugar levels are normal, blood sugar level 7.1, he will repeat the test again for blood
-     DVT start at age 23, ulcers appeared at age 26
-     Heart history is normal
-     Sleeping pattern are normal
-     Eating pattern are normal
-     Used to drink alcohol but stopped in 2010.
-     Breathing is normal
For 20 years, the treatment was limited, he just used regular water and hydrogen peroxide to clean it. He did go to the doctors, but they didn’t help much. For past 6 years, if the wound leaks, he uses hydrogen peroxide, cleans of the edges of the wound, cleans the middle and then applies either sulfanilamide or his urine. Sometimes it works sometimes its not.
-     When his touching his calf it hurts, if he grabs the calf and applies pressure it hurts 10/10. If someone punches the calf lightly its 10/10 pain. If he grabs the calf and applies pressure the wound doesn’t leak.
-     Wound leaks on certain days when he walks. He could walk 30 mins and it starts to leak, it can be half a day and it starts to leak, or full day and it starts to leak. Leakage is various on the day, some days its little and some are a lot. (when it leaks, the color is red, seems like blood).
-     If he lifts something heavy the wound starts to leak
He started smoking in 1985-1990 casually, one cigarette per day. From year of 1991 to present, he smokes one pack per day.

Myself I am his Nephew, living in Canada. He got accept to visit Canada. He has a flight book May 6th to arrive to Canada. I want to help my mother to fix his brother injury/wound. What recommendation can you give me for this particular situation. is their certain antibiotic (pills) he can take, is their a surgery that can be done to fix this problem. what is the full treatment process he need to be in order to heal the entire leg?
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Follow up: Dr. Monish De (0 minute later)
My uncle has a severe deep vein thrombosis (DVT). It started in 1996, when he was 26 years old. He broke his leg, doctors applied cast, after remove of the case, the leg started to inflate (become bigger and bigger). During year of 1996, doctors said that inflation of the leg is normal and mention it will heal on its own. In 1997, he started experiencing ulcers on his calf it was small dot but now as you can see on the pictures it big. At the present time my uncle is 49 years old.
Right leg DVT/ulcer
His height is: 193 cm or 6”3
Weight: 142 kg or 313 pounds
The length of the ulcers wound is 2.7 inch by width 1.9 inches, depth of the wounds is approximately 1-2mm
-     Feeling fatigue/restless when he walks to much
-     Blood pressure is 130/80
-     Urine sugar levels are normal, blood sugar level 7.1, he will repeat the test again for blood
-     DVT start at age 23, ulcers appeared at age 26
-     Heart history is normal
-     Sleeping pattern are normal
-     Eating pattern are normal
-     Used to drink alcohol but stopped in 2010.
-     Breathing is normal
For 20 years, the treatment was limited, he just used regular water and hydrogen peroxide to clean it. He did go to the doctors, but they didn’t help much. For past 6 years, if the wound leaks, he uses hydrogen peroxide, cleans of the edges of the wound, cleans the middle and then applies either sulfanilamide or his urine. Sometimes it works sometimes its not.
-     When his touching his calf it hurts, if he grabs the calf and applies pressure it hurts 10/10. If someone punches the calf lightly its 10/10 pain. If he grabs the calf and applies pressure the wound doesn’t leak.
-     Wound leaks on certain days when he walks. He could walk 30 mins and it starts to leak, it can be half a day and it starts to leak, or full day and it starts to leak. Leakage is various on the day, some days its little and some are a lot. (when it leaks, the color is red, seems like blood).
-     If he lifts something heavy the wound starts to leak
He started smoking in 1985-1990 casually, one cigarette per day. From year of 1991 to present, he smokes one pack per day.

Myself I am his Nephew, living in Canada. He got accept to visit Canada. He has a flight book May 6th to arrive to Canada. I want to help my mother to fix his brother injury/wound. What recommendation can you give me for this particular situation. is their certain antibiotic (pills) he can take, is their a surgery that can be done to fix this problem. what is the full treatment process he need to be in order to heal the entire leg?
doctor
Answered by Dr. Monish De (5 hours later)
Brief Answer:
Apixaban twice daily orally

Detailed Answer:
Hi

I have gone through your uncles history and photos and since his dvt is leaking would advise him to take a new drug called apixaban twice daily for 3 months orally. It prevents blood clot formation and inhibiting factor Xa which helps in formatin of thrombin for blood clotting.

Also he can use compression stockings and practice keeping his legs raised during his flight which would prevent leakage from dvt

Regards
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
doctor
Answered by Dr. Monish De (0 minute later)
Brief Answer:
Apixaban twice daily orally

Detailed Answer:
Hi

I have gone through your uncles history and photos and since his dvt is leaking would advise him to take a new drug called apixaban twice daily for 3 months orally. It prevents blood clot formation and inhibiting factor Xa which helps in formatin of thrombin for blood clotting.

Also he can use compression stockings and practice keeping his legs raised during his flight which would prevent leakage from dvt

Regards
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Monish De (16 hours later)
Thank you for your respond, flying in high altitude wont effect is DVT?

Also, is their a surgery that can fix the DVT? As well as, as you saw on the side edges of the wound he has pose infection, formation every time, what other creams can he use to clean it and fixing it, I assuming the liquid that is leaking it a discharge

What way of methods would you recommend using to heal the ulcer?
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Follow up: Dr. Monish De (0 minute later)
Thank you for your respond, flying in high altitude wont effect is DVT?

Also, is their a surgery that can fix the DVT? As well as, as you saw on the side edges of the wound he has pose infection, formation every time, what other creams can he use to clean it and fixing it, I assuming the liquid that is leaking it a discharge

What way of methods would you recommend using to heal the ulcer?
doctor
Answered by Dr. Monish De (10 hours later)
Brief Answer:

Put vena cava filter.

Detailed Answer:

Hi

Surgery to fix dvt includes putting vena cava filter.

The filter is inserted inside a large vein called the vena cava.

The filter catches blood clots before they travel to the lungs which prevents pulmonary embolism.

However the filter does not stop new blood clots from forming.

Your uncle needs to take antibiotic ciprofloxacin 500 mg twice daily for 7 days for controlling the infection in his leg wound along with application of Mupirocin cream topical locally

The risk of developing DVT while traveling is low.

The risk increases if the travel time is longer than 4 hours

Walk up and down the aisles of airplane.

Move his legs and flex and stretch his feet to improve blood flow in his calves.

Wear loose and comfortable clothing.

Drink plenty of fluids and avoid alcohol.

Wear compression stockings while traveling and take a blood thinning medicine before traveling.

To help his ulcer heal more quickly keep active by walking regularly.

Whenever he is sitting or lying down keep his affected leg elevated with his toes level with his eyes.

Regards
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
doctor
Answered by Dr. Monish De (0 minute later)
Brief Answer:

Put vena cava filter.

Detailed Answer:

Hi

Surgery to fix dvt includes putting vena cava filter.

The filter is inserted inside a large vein called the vena cava.

The filter catches blood clots before they travel to the lungs which prevents pulmonary embolism.

However the filter does not stop new blood clots from forming.

Your uncle needs to take antibiotic ciprofloxacin 500 mg twice daily for 7 days for controlling the infection in his leg wound along with application of Mupirocin cream topical locally

The risk of developing DVT while traveling is low.

The risk increases if the travel time is longer than 4 hours

Walk up and down the aisles of airplane.

Move his legs and flex and stretch his feet to improve blood flow in his calves.

Wear loose and comfortable clothing.

Drink plenty of fluids and avoid alcohol.

Wear compression stockings while traveling and take a blood thinning medicine before traveling.

To help his ulcer heal more quickly keep active by walking regularly.

Whenever he is sitting or lying down keep his affected leg elevated with his toes level with his eyes.

Regards
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Monish De (2 hours later)
Thank you for your reply,

What are some blood thinners can you recommend taking that can be bought of the shelf that are not prescribed by the doctor?

Based on his condition as you seen the photos, how long can the treatment take base on following the steps of taking apixaban twice daily for 3 months orally, ciprofloxacin 500 mg and Mupirocin cream?

Because his 313 pounds plus smokes cigarettes a pack per day, if he losses weight plus eliminates from smoking a pack cigarettes to smoking to low as 1-2 cigarettes per day will it help to heal the ulcer wound/DVT much faster way?

In my understanding, before applying the Mupirocin cream, he must clean the wound at first, once I clean all of the sides and the middle then I apply the cream correct? Also, the leak, that is discard of dead blood cells/infection? if so, can he just let it drain and then apply the cream? Also, he said when he scraps the side it hurts him badly, you think he can take some NSAIDS to feel the pain less for cleaning the wound.?
default
Follow up: Dr. Monish De (0 minute later)
Thank you for your reply,

What are some blood thinners can you recommend taking that can be bought of the shelf that are not prescribed by the doctor?

Based on his condition as you seen the photos, how long can the treatment take base on following the steps of taking apixaban twice daily for 3 months orally, ciprofloxacin 500 mg and Mupirocin cream?

Because his 313 pounds plus smokes cigarettes a pack per day, if he losses weight plus eliminates from smoking a pack cigarettes to smoking to low as 1-2 cigarettes per day will it help to heal the ulcer wound/DVT much faster way?

In my understanding, before applying the Mupirocin cream, he must clean the wound at first, once I clean all of the sides and the middle then I apply the cream correct? Also, the leak, that is discard of dead blood cells/infection? if so, can he just let it drain and then apply the cream? Also, he said when he scraps the side it hurts him badly, you think he can take some NSAIDS to feel the pain less for cleaning the wound.?
doctor
Answered by Dr. Monish De (4 hours later)
Brief Answer:

Apixaban twice daily for 6 months orally course

Detailed Answer:

Hi

He can take blood thinners such as warfarin and dabigatran

Apixaban twice daily for 6 months orally course

Antibiotic around 14 days

Cutting down on cigarettes will definitely help in heal of ulcer

Yes he must clean wound first with normal saline and betadine solution and then apply cream

Yes he can let it drain and then apply cream

NSAIDS can help in reducing pain

Regards
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
doctor
Answered by Dr. Monish De (0 minute later)
Brief Answer:

Apixaban twice daily for 6 months orally course

Detailed Answer:

Hi

He can take blood thinners such as warfarin and dabigatran

Apixaban twice daily for 6 months orally course

Antibiotic around 14 days

Cutting down on cigarettes will definitely help in heal of ulcer

Yes he must clean wound first with normal saline and betadine solution and then apply cream

Yes he can let it drain and then apply cream

NSAIDS can help in reducing pain

Regards
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
Answered by
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Dr. Monish De

Oncologist

Practicing since :2004

Answered : 2229 Questions

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My Uncle Has A Severe Deep Vein Thrombosis (DVT). It

My uncle has a severe deep vein thrombosis (DVT). It started in 1996, when he was 26 years old. He broke his leg, doctors applied cast, after remove of the case, the leg started to inflate (become bigger and bigger). During year of 1996, doctors said that inflation of the leg is normal and mention it will heal on its own. In 1997, he started experiencing ulcers on his calf it was small dot but now as you can see on the pictures it big. At the present time my uncle is 49 years old. Right leg DVT/ulcer His height is: 193 cm or 6”3 Weight: 142 kg or 313 pounds The length of the ulcers wound is 2.7 inch by width 1.9 inches, depth of the wounds is approximately 1-2mm - Feeling fatigue/restless when he walks to much - Blood pressure is 130/80 - Urine sugar levels are normal, blood sugar level 7.1, he will repeat the test again for blood - DVT start at age 23, ulcers appeared at age 26 - Heart history is normal - Sleeping pattern are normal - Eating pattern are normal - Used to drink alcohol but stopped in 2010. - Breathing is normal For 20 years, the treatment was limited, he just used regular water and hydrogen peroxide to clean it. He did go to the doctors, but they didn’t help much. For past 6 years, if the wound leaks, he uses hydrogen peroxide, cleans of the edges of the wound, cleans the middle and then applies either sulfanilamide or his urine. Sometimes it works sometimes its not. - When his touching his calf it hurts, if he grabs the calf and applies pressure it hurts 10/10. If someone punches the calf lightly its 10/10 pain. If he grabs the calf and applies pressure the wound doesn’t leak. - Wound leaks on certain days when he walks. He could walk 30 mins and it starts to leak, it can be half a day and it starts to leak, or full day and it starts to leak. Leakage is various on the day, some days its little and some are a lot. (when it leaks, the color is red, seems like blood). - If he lifts something heavy the wound starts to leak He started smoking in 1985-1990 casually, one cigarette per day. From year of 1991 to present, he smokes one pack per day. Myself I am his Nephew, living in Canada. He got accept to visit Canada. He has a flight book May 6th to arrive to Canada. I want to help my mother to fix his brother injury/wound. What recommendation can you give me for this particular situation. is their certain antibiotic (pills) he can take, is their a surgery that can be done to fix this problem. what is the full treatment process he need to be in order to heal the entire leg?