Is Botox Effective At Treating A Pronounced Limp Due To Cerebral Palsy?
Cerebral palsy spasticity management
Detailed Answer:
Hi XXXXXXX grillo, thanks for asking from HCM.
I can understand your concern. Mild cerebral palsy can cause mild spasticity as you are experiencing it. The spasticity severity is also related to emotions or mental stress. With anxiety/nervousness, it can increase. Thats why you are having increased tightness with mental stress.
You want to know about "Botox". Botox is a kind of neurotoxic poison which is used to treat spasticity. It is injected into neuro-musclular endings in very small dose and causes decrease in tone. Thats how it reduces spasticity. You can opt for it. But remember few points
- Its effect is temporary. Maximum results are seen between 3-5 weeks and results start disappearing by 3 months.
- Temporary weakness of limbs can occur after injection. It will subside.
- Repeat injection are needed after 6-8 weeks.
- The local injection site can become very painful.
So before going for it, discuss everything with your doctor.
Hope it will help. If you need any help, do let me know.
Thanks. Take care.
Oral medication and other treatment of Spasticity
Detailed Answer:
Hi XXXXXXX grillo, welcome back.
Nowadays, there are many oral medications which can help in spasticity. Baclofen is the most commonly prescribed drug. It can cause some sedation but its addiction profile is poor. So don't worry about it. Long-term use of Baclofen can cause damage to kidney, generalized muscle weakness, fatigue, nausea, and vomiting. So take this drug under supervision.
Other oral medication which can also reduce spasticity -
- Benzodiazepines like clonazepam/Diazepam can reduce muscle spasticity, anxiety and stress (reduction of precipitating factors). However, these can cause some addiction.
- Central acting muscle relaxants like Tolperisone, Tizanidine which reduces muscle tone or sympathetic outflow.
-Dantrolene - This is a peripherally acting medication that prevents calcium release from the sarcoplasmic reticulum. It is particularly effective in cerebral-origin spasticities, such as that occurring in traumatic brain injury (TBI), stroke, or cerebral palsy.
- Intrathecal Baclofen pump can also help in reducing spasticity. A permanent implant is placed near the spinal cord and nerves to release the regular small amount of Baclofen. It is effective for a long term.
You can discuss above options with your doctor. After it, you can start oral medication. If no relief with it, then other measures like Botulinum injection or Baclofen pump can be considered.
Hope it will help you. If you are having any doubts, do let me know.
Thanks.
Take care.
Alcohol effect on spasticity
Detailed Answer:
Hi XXXXXXX grillo, welcome back.
Thank you, much appreciated.
Alcohol is a central nervous system depressing drug acts via GABA agonistic action (like Benzodiazepines). Due to this action, it reduces spasticity to some extent. That is the reason behind lightness in legs.
Next day, you feel more tightness due to weaning off alcohol effect. That might be the possible explanation. There is no other explanation about it in medical literature.
Hope it will answer your query. If any doubt, do let me know.
Thanks. Take care.