Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

197 Doctors Online
Doctor Image
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

Is Zanocin intake safe and effective for treatment of UTI in an elderly patient?

Answered by
Dr.
Dr. Vaishalee Punj

General & Family Physician

Practicing since :2003

Answered : 2029 Questions

default
Posted on Wed, 6 Aug 2014 in Medicines and Side Effects
Question: ZANOCIN 400 ONE TABLET/DAY HAS BEEN ADMINISTERED FOR CONSECUTIVE 10 DAYS ON A 76 YEARS OLD MALE DIABETIC FOR TREATING URINARY INFECTION. IS IT OVERDOSE AND HARMFUL?
doctor
Answered by Dr. Vaishalee Punj 13 minutes later
Brief Answer:
Zanocin is ofloxacin

Detailed Answer:
Hi
Thanks for your query.

It was better if you provided his weight.

If we just consider his age, some studies have shown that ofloxacin tends to accumulate in elderly people (for many reasons), thus the dose should be reduced to half that would be given to a younger person of same weight.

Research has also shown that ofloxacin is safe for use in elderly and can be used in the dose range of 400 to 800 mg a day.

Thus I would not be worried. If his weight is lower than IBW (around 70 kg), please let me know.

Hope it helps.

Dr Vaishalee
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
default
Follow up: Dr. Vaishalee Punj 12 days later
Patient Details : 76 years old about 85 kg weight male diabetic,hypertensive, with old small several cerebral infarcts,lumber spondylosis & spinal stenosis
Ongoing treatment for urinal infection etc :
1.Amaryl2mg OD 2.Amaryl 1mg OD 3.Gluformin XL 1gm OD 4.Zanocin 200 BD
UrimaxD OD 5.ReciperL BD 6.Asomex5 OD 7.Ecosprin75 OD 8.Storvas20mg OD 9.Citicholine500mg BD Trinergic OD 10.Meropenem 1gm TDS x 5days
Sodium level of the patient cannot be maintained. It gets down frequently causing discomfort and drowsiness to the very weak bed ridden patient. Use of hyper tonic saline (3% sodium chloride NS) raise the sodium level to 132-135 MMOL/L only to bring down the level to 98-105MMOL/L with in 36 hours. Oral supplement with common salt (20gm/day) and conversing drinking water to ORS is in force. Presently His BP 110/60 , creatinine 1.6 Potassium-4.8 What to do to stabilize the sodium level?
doctor
Answered by Dr. Vaishalee Punj 13 hours later
Brief Answer:
My advice as follows

Detailed Answer:
Hi again

It seems that this patient has chronic hyponatremia. Since he does not seem to have many symptoms. Still his sodium levels need to be maintained.

My advice is as follows:

1. Find the cause of hyponatremia. The treatment of the cause can bring about a lot of difference. Causes can be many. Investigations can be carried out under the supervision of an nephrologist. Amlodipine may be contributing a little to sodium loss.

2. Rapid deterioration and rapid correction are damaging to the brain. The saline infusions should be slow keeping in consideration the volume status of the patient. The infusion should bring the level up by 12 meq/l over a period of 24 - 36 hours. Careful use of hypertonic saline can be life-saving.

The level is to be maintained after bringing it to this level. It can be maintained with supplementing with salt and ORS (appropriate concentrations), fluid restriction. While restricting fluids, we need to target the sodium levels and not the fluid status of the patient.

This needs regular supervision.

3. Correction of the volume. The patient maybe hypovolemic, euvolemic or hypervolemic. The hypo- and the hyper volemic states are to be corrected (while keeping a close look on sodium levels).

Hope it helps.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
premium_optimized

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions ,   ,  
Drug/Medication ,  
Medical Topics

Recent questions on  Spinal stenosis

doctor1 MD

I had an mri completed and the found degerative changes in the lower spine with osteopyte formation and narroewing in some areas I also have a right shoulder pain and neck pain with a drooping eye which they found no explanation for. Does this mean i have osteoarthritis of the spine?

doctor1 MD

I have spinal stenosis lorodisis degenerative disc disease I have had two lumbar surgeries a cervical fusion. Nerve damage to my left foot. Nerve damage at my c6-7 level. Suffer from headaches, chronic pain, depression , spondylitis what can I do for pain. Currently taking cymbalta ?

doctor1 MD

My mother is 80 years old. She has had Myasthenia Gravis for over 55 years and has been in a wheelchair most of that time. A few years ago she was diagnosed with Parkinson’s. This past year she began feeling pain in her neck and shoulder and was told it was spinal stenosis. She has successfully used Prostigmine for years to help with her muscle weakness, however it become unavailable this past summer so she switched to Mestinon for 6 months. She did not do very well on the Mestinon. Her muscles were weak and she was not as mentally sharp as she normally is – I kept thinking her sodium was low. During the 6 months she was on the Mestinon she fell out of her wheel chair and hit her head on the bathroom sink giving her mild subdural hematoma. An MRI was done and everything looked ok. After all this her neck dropped forward. Over about a 3 month period her head dropped and is causing her pain and discomfort and making eating and swallowing difficult due to the forward position of her neck. Her facial muscles are not weak. Her neurologist performed an EMG and there was evidence of mild exacerbation of MG symptoms. Meanwhile we found some Prostigmine and switched her from Mestinon back to Prostigmin. Her mind clarity improved immediately and her muscle strength improved enough so that she is again able to transfer herself from chair to wheelchair, but her head is still dropped. She tried IVIG treatment but that did not help. She’s considering plasma apheresis which helped her about 30 years ago during a difficult MG period. She’s miserable because of her neck but I’m not sure the plasma apheresis will help her neck. Any ideas or suggestions to help her?

doctor1 MD

I ve been diagnosed with mild thoracic spinal stenosis.Moderate disc protrusion that compresses the ventral spinal cord. This was due to an accident at work.I fell on my back while trying to get over a 4.5 ft. fence. I m currently trying to receive compensation for the injury. My employers want me to prove that this was the cause of my condition. Is there anything that you could offer that would help me prove that this indeed was the causes of my condition.

doctor1 MD

My wife, age 83, has developed a situation where her dominant hand (left) the index and ring fingers have curled into the palm and those knuckles are swollen . This is very painful with the pain radiating up the arm to the elbow. she has no...

doctor1 MD

I ,ve had arthritis degenerative lumbosacral degenerative disc disease with strain for many years, recently I developed arthritis is the spine, and subsequently spinal stenosis . Are the 3 health issues relater and how? For example can one lead...

doctor1 MD

Hello, I have been attending therapy with a chiropractor for about 6 treatments for a pinched nerve along with spinal stenosis . Should I change a go to an orthopedic center for other observation? It seems as though after 6 weeks, I am not getting...