question-icon

Is Alendronate Cause Damage To The Esophagus?

default
Posted on Wed, 19 Oct 2016
Question: About alendronate, I already have some little trouble in swallowing food in the morning, due to dryness.(I live in the high desert). Will I be OK with this drug? I read that it can cause damage to esophagus.
doctor
Answered by Dr. Aashish Raghu (11 minutes later)
Brief Answer:
Follow certain precautions

Detailed Answer:
Hi there.

It is advisable to consume the Alendronate tablet with a full glass of water 30 minutes before the first meal of the day and then sit in upright position for another 30 minutes.

This reduces the chances of reflux oesophagitis.

Takes this medicine with care and report to your Doctor in case any adverse effects.

I hope I have answered your query.

I will be available to answer your follow up queries.

Regards,

Dr. Aashish Raghu
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
default
Follow up: Dr. Aashish Raghu (11 minutes later)
Thank you, but that is info that I already read on the web site about this drug. I wanted to know what the chances were that I would have adverse reaction, since I already have a dry throat ion the morning and some trouble swallowing food.

Yes, I have read this advice on the web sites for this drug, but can you tell me the likelihood of adverse reaction, because of the fact that I already have dryness of the throat in the morning and some trouble swallowing food if it isn't swallowed with water. The reason I wrote was that i was worried I might damage my esopphagus, because iof the dryness already there.
doctor
Answered by Dr. Aashish Raghu (44 minutes later)
Brief Answer:
You have increased chance of oesophagitis. Exercise caution

Detailed Answer:
Difficulty in swallowing food is a problem that can put you at risk of oesophagitis due to Alendronate. I suggest you get it evaluated by a trained Gastroenterologist.

According to literature, patients being treated on Alendronate were found to have 0.041% chance of being oesophagitis, but depending on the any ongoing oesophageal pathology the chances of oesophagitis seem to increase. This hasn't been quantified yet and heavily depends on what problem you actually have in your oesophagus prior to the Alendronate treatment.

But literature says that caution must be exercised while treating a patient with prior oesophageal pathology on Alendronate.


Above answer was peer-reviewed by : Dr. Yogesh D
doctor
Answered by
Dr.
Dr. Aashish Raghu

Orthopaedic Surgeon

Practicing since :2011

Answered : 5448 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

152 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Is Alendronate Cause Damage To The Esophagus?

Brief Answer: Follow certain precautions Detailed Answer: Hi there. It is advisable to consume the Alendronate tablet with a full glass of water 30 minutes before the first meal of the day and then sit in upright position for another 30 minutes. This reduces the chances of reflux oesophagitis. Takes this medicine with care and report to your Doctor in case any adverse effects. I hope I have answered your query. I will be available to answer your follow up queries. Regards, Dr. Aashish Raghu