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Does Intake Of Anti-retroviral Medicines Help In Preventing HIV?

Posted on Fri, 10 Jun 2016

Question: HI

I AM 31 MALE HAD SEX WITH CALL GIRL BY 7 DAYS BACK , ACCIDENTLY MY CONDOM BROKE DOWN , SHE HAD ORAL SEX WITH CONDOMS ALSO.,
I AM SCARED OF GETTING HIV AND I ASKED HER CHECK FOR HIV ANTIBODIES WHICH CAME NEGATIVE FOR 1 AND 2 ( CARD TEST) AND ALSO NEGATIVE PROVIRAL DNA HIV -1 ,

I HAVE TESTED ME FOR P24 ANTIGEN AND HIV RNA1 , HIV RNA2 AND PROVIRAL DNA AND HIV DUO WHICH ALL COMES NEGATIVE

PLEASE LET ME KNOW WHETHER I HAVE START ANY ANTI RETROVITRAL TO AVOID HIV

Answered by Dr. Sunil Jangid (1 hour later)

Brief Answer:
Anti-retroviral medicines are not recommended in your case.

Detailed Answer:
Dear XXXX,

Welcome to HCM. I have gone through your query and understand the concern you are worried about. Being your physician try to solve it at the earliest.

You had protected sex with call girl but thecondom was broken then the risk of getting HIV is there but the chances are very less with single exposure.

All your test results for HIV like P24 antigen, RNA PCR, proviral DNA and HIV Duos all are negative among with negative card test for call girl then no need to get worried or so much anxious for HIV.

Anti-retroviral medicines are not recommended in such cases as 72 hours had already passed. You need to go for repeat testing after one month to get more reliable and accurate result.

Hope this info will help you. If still any query left in your mind feel free to ask me and I am here to help you always. Wishing you very happy life ahead.

Thank You

Above answer was peer-reviewed by : Dr. Arnab Banerjee

Follow up: Dr. Sunil Jangid (10 hours later)

HI SIR

FOR THAT CALL GIRL ONLY HIV ANTIBODIES AND PROVIRAL DNA IS NEGATIVE

FOR ME HIV DUO, PROVIRAL DNA , RNA HIV 1 AND 2 , P24ANTIGEN IS NEGATIVE

LET ME KNOW ANY OTHER TEST I HAVE TO CONFIRM IT BY 2ND WEEK

I HAVE STARTED ALREADY 4 DRUG REGIMEN AS PREVENTIVE DUOVIR E KIT AND XXXXXXX BEFORE 72 HOURS

PLEASE ADVICE

Answered by Dr. Sunil Jangid (1 hour later)

Brief Answer:
Go for 4th generation HIV Duos after one month.

Detailed Answer:
Dear Partibhan,

Welcome back and thanks for follow-up.

If you had started PEP within 72 hours then forget about the girl's status and continue it for one month. Go for 4th generation HIV Duos test after 1 month and then after 3 months as per routine guidelines to get 100% conclusive and reliable result.

Thank You

Above answer was peer-reviewed by : Dr. Sonia Raina

Follow up: Dr. Sunil Jangid (5 hours later)

CURRENTLY ON

LAMUVIDUNE ZIDOVIDUNE , TENOFOVIR AND EFAVIRENAZ.,

I HAVE LOT OF SIDE EFFECTS WHEN TAKING EFAVIRANAZ ( SLEEPY , DEPRESSION,
MOODY ETC) ITS WORTHY TO TAKE THAT OR ELSE SHALL STOP EFAVIRANAZ
IF SO PLEASE SUGGEST SOME ALTERNATIVE

Answered by Dr. Sunil Jangid (36 minutes later)

Brief Answer:
CNS side effects are common with Efavirenz.

Detailed Answer:
Dear XXXXXXX

Welcome back once again.

Depression, mood swings and sleepiness all these side effects are common with Efavirenz, that is why it is recommended to take this drug at night while going to sleep. If still you are not comfortable then better to stop the drug after an expert opinion. Forget the past and move ahead in life. Stay happy and healthy.

Thank You

Above answer was peer-reviewed by : Dr. Deepak

Follow up: Dr. Sunil Jangid (15 hours later)

FINAL QUESTION DR

WHICH TEST ARE RELIABLE IN EARLY DETECTION

PROVIRAL DNA

OR

P24 ANTIGEN

OR

HIV RNA RT PCR

OR HIV DUO AND ALSO EXPLAIN THE DETECTABLE PERIOD

Answered by Dr. Sunil Jangid (1 hour later)

Brief Answer:
P24 antigen or HIV Duos test.

Detailed Answer:
Dear XXXXXXX

P24 antigen and HIV Duos tests are more accurate and reliable in early period even after two weeks of infection so get tested to confirm your status.

Thank You

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Sunil Jangid (2 days later)

HI DOCTOR

I REQUESTED SOURCE TO CHECK EARLY HIV SCREEN ( HIV P24 ANTIGEN+ HIV ANTIBIODIES ) METHOD CMIA .,
WHICH SHOWS NON REACTIVE ., ( 7 DAYS AFTER EXPOSURE)
FROM SRL XXXXXXX

AND MINE HIV DUO 4TH GENERATION TEST 8 DAYS AFTER EXPOSURE NON REACTIVE .,

IS THERE ANY THING TO BE DONE AND HOW TO STOP ART

PLEASE REPLY

Answered by Dr. Sunil Jangid (40 minutes later)

Brief Answer:
You need to go for repeat test after one month.

Detailed Answer:
Dear XXXXXXX

You and your partner both negative for HIV after one week and the risk is very less in your case then you can stop ART but better to continue it for 1 month.

As per routine guidelines you need to go for repeat test after one month and then again after 3 months to get 100% conclusive and accurate result.

Don't get anxious or feared as it is just routine protocol which every one with any exposure has to follow nothing else so be relaxed and move ahead in life.

Thank You

Above answer was peer-reviewed by : Dr. Sonia Raina

Follow up: Dr. Sunil Jangid (26 minutes later)

WHETHER LAMUVIDONE ZIDOVIDUNE AND TENOFOVIR ENOUGH OR
TO REDUCE OR INCREASE

PLEASE ADVICE

Answered by Dr. Sunil Jangid (2 hours later)

Brief Answer:
It is enough.

Detailed Answer:
Dear XXXXXXX

The combination of Zidovudine, Lamivudine and Tenofovir is well enough and nothing to add any thing more. Complete it for 4 weeks than go for the test as per protocol.

Thank You

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Above answer was peer-reviewed by : Dr. Sonia Raina