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Does Venlafaxine Interact With Zoloft?

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Posted on Thu, 27 Apr 2017
Question: I was on venlafaxine 300 mg. was not working so dr changed it to zoloft. took 150mg venlafaxine for a week then 75 mg with 50 mg of zoloft. then just 50mg of zoloft. I got diahrea upset stomach and referral pain to my sholder which is worse than an 8 on a ten scale. Now I have right quadron pain especially under my ribs. Is all this pain from going off venlafaxine and taking zoloft?
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Answered by Dr. Seikhoo Bishnoi (40 minutes later)
Brief Answer:
The pain is probably occurring due to Zoloft.

Detailed Answer:
Hello thanks for asking from HCM

I can understand your concern. Zoloft is Sertraline and is a SSRI drug. It's is normal to see diarrhoea and gastric upset as side effects when the drug is started. In most individuals these adverse effects last for about a week or two. I don't think withdrawal of Venlafaxine is the reason of these side effects. The pain in right quadrant is also probably occurring due to Zoloft. The pain will decrease by own in some days. No need to worry. If pain persists then talk to a doctor for evaluation.

Thanks and Take care.
Note: For further guidance on mental health, Click here.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Seikhoo Bishnoi

Psychiatrist

Practicing since :2007

Answered : 5193 Questions

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Does Venlafaxine Interact With Zoloft?

Brief Answer: The pain is probably occurring due to Zoloft. Detailed Answer: Hello thanks for asking from HCM I can understand your concern. Zoloft is Sertraline and is a SSRI drug. It's is normal to see diarrhoea and gastric upset as side effects when the drug is started. In most individuals these adverse effects last for about a week or two. I don't think withdrawal of Venlafaxine is the reason of these side effects. The pain in right quadrant is also probably occurring due to Zoloft. The pain will decrease by own in some days. No need to worry. If pain persists then talk to a doctor for evaluation. Thanks and Take care.