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Can Hiv Remain Undetected Till 90 Days After Exposure?

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Posted on Mon, 21 Apr 2014
Question: Hi Doctor, How are you. I had a unprotected oral sex as a receiver from a lady of unknown HIV status on 24th November 2013. after that incident I have had total 8 HIV test's including 2 XXXXXXX test's .kindly see below with timing as mentioned. Received unprotected oral November 24th 2013 Putting all the test's to gether 1.rapid test after 15th day exposure -negative 2. Cmia test after 17th day exposure -negative 3. XXXXXXX after 20th day - XXXXXXX screening done for viral RNA/DNA HBV : NOT DETECTED HCV :NOT DETECTED HIV 1/2 :NOT DETECTED 4. Elisa ( 4 generation as informed by lab to me ) - 33rd day Non - Reactive . 5. XXXXXXX after 57th day - XXXXXXX screening done for viral RNA/DNA HBV : NOT DETECTED HCV :NOT DETECTED HIV 1/2 :NOT DETECTED Exactly 90 days after my exposure: 6. Rapid card which they use in my sister's blood bank =negative 7. Cmia Method ( Hiv 1 & 2 ) = .17 (Non-reactive) 8. Hiv 1 & 2 + P 24 = Negative ( In a different lab ) As far as other STD's I have done VDRL - Rapid card total 4 times 2 times I have done complete urine test I have discussed the scenario with respected Dr XXXXXXX in (HGM) already he said I am totally fine no need for further testing .So I feel bad again to ask him Doubt. Issue is 1.I am having severe cold and fever for the past 2 weeks 2.boils in my armpit 3.Rashes in hands & legs itching. 4.I have some bulgy round boil like thing in my left and right arm joint area ( is it lymp node swelling ) Doubt's: 1.I had the habit of having chewable tobacco for past 12 years can it affect my result any how. 2.I have been taking AZITHROMYCIN for the past 60 days when my test's were taken will it have any effect on my result's 3.Can Hiv remain undetected till 90 days after the contact that to after having 8 test's. 4.The bodily condition's I am facing is it related to hiv. All the test's were done in different time and in different lab's. Regard's XXXX
doctor
Answered by Dr. Sankaranantham Murugan (24 minutes later)
Brief Answer: Superior tests done for you could not miss HIV. Detailed Answer: Hi XXXXXXX Welcome back . It Is once again me. All the test done by you especially around 90 days after your risky contact are highly sensitive and have a very high specificity for HIV including CMIA and P24 antigen test. The antigen test appears as early as possible within a week and well detectable within 4 weeks and conclusive and never affected by body immune system or your habits like tobacco chewing. If it remains negative even after ninety days means that there could not be any chance of missing HIV infection if it occurred already. Azithromycin has no effect on virus and it is an antibiotic. So it could not interfere with either antibody test or antigen test. So there is no chance of missing HIV from your body. Fever, rashes in hand, boils can occur to anybody. Consult your physician and get cured from the same. Forget about HIV totally. Dr S.M
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sankaranantham Murugan (19 minutes later)
Sir, Did not tend to double check .. Felt bad to ask you again after you have told me number of times I am free from HIV & other STD's. But feeling happy after receiving reply from your side Sir. Sir I am not putting up any debate some doubt's: 1. Sir i read in a article that P24 are at its best for first few weeks that's why. 2. Some of doctor's in HGM are suggesting 6 & 12 months( but they are not hiv specialist as I found) test should be done i read it today morning which put me in more puzzle. 3. Sir after the HIV enters the body will it immediately connect and start producing copies or will it lie dormant for some time and then start multiplying (just for knowledge if you want to answer) All was going good sir I was completely off this topic had intercourse with my wife till this boil's and fever came up I got panicking .Then the sex with my wife put me in more pressure thinking I have infected her. I am as doing some meditation's also went to some of holy place I was completely clear .. Some reading today morning put me in pressure .. Sorry Sir. Regard's XXXX
doctor
Answered by Dr. Sankaranantham Murugan (31 minutes later)
Brief Answer: Still you are not infected. Detailed Answer: Hi XXXXXXX Don't feel bad. I am enjoying your questions. P24 antigen test will be present for a short while only as you mentioned, but not for weeks, persists for few months. At 90 days it will be reliable. Moreover you had this test as 4th generation test at 33 days that also negative.4th generation test also incorporated with P24 antigen. So you need not worry at all. Oral sex carry a very lowest risk for HIV that too as a receiver. HIV after enters into body it gets established in human body system (CD4 Cells) within 72 hours. Then it actively starts multiplying inside the cell. If there are hundreds of cells with active multiplication, there may be one or two in a stage of dormant state. Don't try to analyze the situation. believe that you are not infected. Dr S.Murugan
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sankaranantham Murugan (18 minutes later)
Hi Sir, Thank's for the reply. I have taken 3 test's at 90 day's mark 1 rapid + 2 test's ( Cmia + Hiv1/2 + P24 ) I think it is high timing to turn positive. more over all the 3 test's cannot be false negative. Sir i have done 2 test's for XXXXXXX Viral RNA & DNA also 20th and 57th day after the oral incident. I think it looks for the virus itself .. Cmia = 2 times XXXXXXX = 2 times Rapid = 2 times Hiv1 /2 + P24 = 1 time Elisa = 1 time All negative so I should be negative Sir do you recommend any further test seeing this scenario of boils and rashes. Sorry once again sir any were I have gone wrong or wrote some thing wrong. Regard's XXXX
doctor
Answered by Dr. Sankaranantham Murugan (5 hours later)
Brief Answer: No further test is necessary for you. Detailed Answer: Hi XXXXXXX Now you are thinking in the right direction. Yes. As you said all the test can not be false negative. All the tests are highly reliable and some of the tests are highly specific and improved technology like XXXXXXX and CMIA. So your symptoms have nothing to do with HIV. I never advise you to have further test. Dr S.Murugan
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sankaranantham Murugan (19 hours later)
Hi sir, Good evening. I have a last and final doubt say like confession also I have had 4 times protected intercourse with different CSW in dubai before my marriage (with out knowledge of hiv) in 2008 then tested in 2009 before marriage consulted with a doctor in chennai he said I am ok to get married as all the sex was protected I was not in much worry and got married after that I was truthful to my wife till this incident happend .. Will the current 8 tests I have taken will cover the past incident also or WILL ANTIBODY & ANTIGEN go to UNDETECED levels after some time . Felt ashamed to tell you the previous incidents sorry sir. The before marriage acts were like bachelor life with friends I did that mistake felt like confessing it to go so you can give me a better judgement sir because these incidents are also putting me in pressure like if I was infected in past may be .. Due you still advice no need for further tests. Sorry sir dont mistake me I should have told you this long back it self .. This will be my last question sorry sir. XXXX
doctor
Answered by Dr. Sankaranantham Murugan (5 hours later)
Brief Answer: 8 negative tests covered the distant past of yours Detailed Answer: Hi XXXXXXX Nothing to feel ashamed or guilty. Many of us will have a past. As your physician told with protected sex you are safe. Certain type of Antigen may disappear after the appearance of certain antibodies (Not all antigens). But antibodies will be present as long as the infection persists and certain other types of antibodies would be there even after a complete cure either life long or for years together like antibodies against Chicken pox etc. So there is no doubt that the negative tests of HIV done for you had covered your whole life till the dates of these tests ensure you that you are HIV free. So forget about the past and HIV totally and go ahead happily in the future and stick to safe sex for ever. Dr S.Murugan
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sankaranantham Murugan (13 minutes later)
Hi sir, Thank you for the reply. I am indeed stupid or immature at that time I was young. After marriage I did not go out of box only in the present incident as u advice antibodies are detectable for life time so all my antibodies are negative with this reply I have come to complete relax mode. Regarding safe sex I will not ever go to another lady this past 4.5 months have tought me how valuable and short is our life and I dont want to be a person to infect my lovable family for my pleasure .. So sir I Have planned for 2nd kid I have started having intercourse with my wife already . So I will not test further. . Happy week end sir. XXXX
doctor
Answered by Dr. Sankaranantham Murugan (6 hours later)
Brief Answer: Most welcome. Detailed Answer: Hi XXXXXXX It is nice to hear from you positive attitude. Nothing to worry. You will have a wonderful future Dr S.Murugan
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Sankaranantham Murugan

HIV AIDS Specialist

Practicing since :1974

Answered : 3112 Questions

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Can Hiv Remain Undetected Till 90 Days After Exposure?

Brief Answer: Superior tests done for you could not miss HIV. Detailed Answer: Hi XXXXXXX Welcome back . It Is once again me. All the test done by you especially around 90 days after your risky contact are highly sensitive and have a very high specificity for HIV including CMIA and P24 antigen test. The antigen test appears as early as possible within a week and well detectable within 4 weeks and conclusive and never affected by body immune system or your habits like tobacco chewing. If it remains negative even after ninety days means that there could not be any chance of missing HIV infection if it occurred already. Azithromycin has no effect on virus and it is an antibiotic. So it could not interfere with either antibody test or antigen test. So there is no chance of missing HIV from your body. Fever, rashes in hand, boils can occur to anybody. Consult your physician and get cured from the same. Forget about HIV totally. Dr S.M