Hi, Potklor syrup is a medication that contains potassium chloride and is commonly used to treat potassium deficiency or low levels of potassium in the blood. It is also used as an adjunctive treatment for periodic paralysis, a condition that causes episodes of muscle weakness or paralysis that can last for several hours or days. Long-term use of Potklor syrup can cause several side effects, including: * Gastrointestinal problems: Nausea, vomiting, and diarrhea can occur in some people who take potassium supplements. These symptoms can usually be managed by adjusting the dose or taking the medication with food. * Heart problems: High levels of potassium in the blood can cause an irregular heartbeat or other heart problems. People with kidney disease or other conditions that affect potassium metabolism may be at increased risk of these side effects. * Kidney problems: Long-term use of potassium supplements can cause kidney damage or other kidney problems, particularly in people with underlying kidney disease. If your husband has been taking Potklor syrup for 15 years and has not experienced any significant side effects, it is unlikely that he will develop any serious problems in the future. However, it is important to monitor his potassium levels and kidney function regularly, especially if he is planning to start a family. You should consult your doctor to discuss any concerns you have about the long-term use of Potklor syrup or other medications your husband is taking for his periodic paralysis. They can advise you on the best course of action and any potential risks associated with these medications. If you require a personalized response, kindly use the Ask A Doctor service and post a follow-up. Take care. Hope I have answered your question. Regards, Dr. Priyanka, General & Family Physician