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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Will Depo Provera Shot Cause Any Side Effects?

Hi, I had my first depo provera shot for suspected endometriosis on sept 19, and started to feel very I ll on 1 dec. Extreme fatigue, nausea, pain, headaches and fuzzy head, crying all the time. I went to the doctor and they didn t say that it could be due to depo. I started to feel a bit better on 5 Jan, but on 12 Jan they advised me to have the next injection so I did. 3 days after the injection all my fatigue and depressions symptoms are back, plus I have itchy spots on my scalp, and my hair is falling out. My progesterone levels taken on 14 dec are 0.7 which I know is very low. If I was told how this drug would make me feel I would not have touched it. Do you think that my symptoms Are due to adrenal fatigue/low progesterone because of the depo? If so, how can I get the drug out of my body quicker, and will my cortisol and progesterone levels rise again once it is out of my body, or will I need to boost them. Thanks Ella
Thu, 28 May 2020
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General & Family Physician 's  Response
Hi,

Fatigue,nausea, pain, headaches and mood changes can be common side effects of Depo shot. Most symptoms reduce in the subsequent cycles. Since your symptoms continue and are more severe, you may have to consider stopping the injection. Once you have stopped the injection, it may take at least 4 weeks for the hormone to be eliminated from the body. You can check your blood hormone levels again for further monitoring and you can use hormonal pills if required.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Saranya Ramadoss, General & Family Physician
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Will Depo Provera Shot Cause Any Side Effects?

Hi, Fatigue,nausea, pain, headaches and mood changes can be common side effects of Depo shot. Most symptoms reduce in the subsequent cycles. Since your symptoms continue and are more severe, you may have to consider stopping the injection. Once you have stopped the injection, it may take at least 4 weeks for the hormone to be eliminated from the body. You can check your blood hormone levels again for further monitoring and you can use hormonal pills if required. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Saranya Ramadoss, General & Family Physician