Dear Welcome to HCM We understand your concerns I went through your details. I suggest you not to worry much. Depakote tablets contain the active ingredient valproate semisodium, which is is a type of medicine called a mood stabiliser. It is used to treat the psychiatric illness bipolar affective disorder, or manic depression. Oleanz contains the active ingredient Olanzapine, an atypical anti psychotic. It is not generally intended to treat mild depression. Sizodon is risperidone. It s an atypical anti-psychotic prescribed for delusional psychosis/schizophrenia, obsessive compulsive disorder, tourette s syndrome, depression, and bipolar disorder. In a nutshell, your wife could be suffering from either bi-polar disorder of mile depression. Both the condition are curable and you should consult a psychiatrist for prescription. If you require more of my help in this aspect, Please post a direct question to me in this website. Make sure that you include every minute details possible. I shall prescribe some psychotherapy techniques which should help you cure your condition further. Hope this answers your query. Available for further clarifications. Good luck.