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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What is the antidote for Dapsone poisoning ?

Hi doctor whats the antidote to dapsone poisoning
Thu, 19 Jan 2012
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Pediatrician 's  Response
Hi
Welcome to HCM
REad your prob, symptoms of depsone poisoning are nausea vomiting,headach drowsiness, cynosis, n convulsion. nausea n vomiting can be treated by diphenhydramin, multi dose of activated charcol given to patients, methylene blue also be given to improve cynosis.
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General Surgeon Dr. Rajinder Bajoria's  Response
Hello
Thanks for your query.     



Long-term administration of dapsone in patients usually results in methemoglobinemia which is not clinically significant.


The hemotoxicity of dapsone is not caused by the drug , but by its metabolites.

There is no specific antidote ,only symptomatic management of methemoglobinemia with methyline blue & folic acids can be done


‘Hope I have answered your query, I will be available to answer your follow up queries, “Wish you Good Health and trouble free speedy recovery”
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What is the antidote for Dapsone poisoning ?

Hi Welcome to HCM REad your prob, symptoms of depsone poisoning are nausea vomiting,headach drowsiness, cynosis, n convulsion. nausea n vomiting can be treated by diphenhydramin, multi dose of activated charcol given to patients, methylene blue also be given to improve cynosis.