Hi & Welcome. The presence of elevated antinuclear antibodies or ANAs are suggestive of autoimmune disease. Your immune system normally makes antibodies to help you fight infection. In contrast, antinuclear antibodies often attack your body s own tissues — autoantibodies specifically targeting each cell s nucleus. Elevated ANAs are the hallmarks of autoimmune diseases like systemic lupus erythematosus, scleroderma, sjögren’s syndrome, polymyositis/dermatomyositis, mixed connective tissue disease, drug-induced lupus, and autoimmune hepatitis. In view of the above possibilities, I would therefore advise you to consult a physician or rheumatologist for proper clinical examination and to find out the exact cause of raised ANAs. Hope these answer your query.