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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does Blood Test Reports Suggest?

i got my blood test done. Widal (tube method) showed O1:80; H 1:160; AH 160; BH 1:80. I took medication Azee 500 for a week and got the blood tests done again and got the following O 1:20, H 1:80; AH 1:160; BH Negative. Is it typhoid? I dont have any fever for last 3 days. Only lose motions. I am also taking 2 velgut capsules each day. Is it typhoid? is it coming down?
Mon, 1 Sep 2014
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Pathologist and Microbiologist 's  Response
Hi!
welcome to HCM!
Traditionally, a positive Widal test is based on a fourfold rise in O agglutinins in repeated tests or a titre of > 1:160 (in endemic areas like India) in a single test. From the sensitivity and specificity data, it is clear that some culture proven cases of typhoid fever may be associated with a negative Widal test particularly if done early in the course of illness, so that the predictive value of negative Widal test is limited. Culture isolation of Salmonella typhi from blood and bone marrow is the standard diagnostic test to confirm typhoid fever.
Your O1:80 did not suggest typhoid.
hope this helps!
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What Does Blood Test Reports Suggest?

Hi! welcome to HCM! Traditionally, a positive Widal test is based on a fourfold rise in O agglutinins in repeated tests or a titre of 1:160 (in endemic areas like India) in a single test. From the sensitivity and specificity data, it is clear that some culture proven cases of typhoid fever may be associated with a negative Widal test particularly if done early in the course of illness, so that the predictive value of negative Widal test is limited. Culture isolation of Salmonella typhi from blood and bone marrow is the standard diagnostic test to confirm typhoid fever. Your O1:80 did not suggest typhoid. hope this helps!