Hi, Shicalm H is a combination medication of both antipsychotic medication called trifluoperazine and anticholinergic drug called trihexyphenidyl that is used to treat schizophrenia. Trifluoperazine is an antipsychotic medication in a group of drugs called phenothiazines used to treat psychotic disorders like schizophrenia. It is well known for increasing prolactin levels, breast swelling and discharge. Anticholinergics drugs like trihexyphenidyl can inhibit lactation in women, apparently by inhibiting growth hormone and oxytocin secretion. It can also reduce serum prolactin that cause nipple discharge or breast milk in non nursing women. Etirest contains etizolam which belongs to the group of medications known as benzodiazepines is used to treat short time anxiety and insomnia. Hyperprolactinoma achieved with the use of Etirest is possibly due to activation of the GABA system which stimulates prolactin release directly or by inhibiting the dopaminergic neurons or alternatively to activation of the endorphinergic system. Raised prolactin levels or hyperprolactinoma can cause breast milk. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Zubayer Alam, General And Family Physician