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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Fatigue While On Hydrocodone?

I ve been on Hydrocode prescribed by a pain management physician, also ive been prescribed clonazepam for anxiety. I recently started taking St. John s Wort for depression as anything else in the past has caused ill effects. My anxiety has increased along with sleepless night and server fatigue. What say you sir?
Mon, 13 Nov 2017
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Ayurveda Specialist,  's  Response
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Thanks for contacting with your health concern

1. Hydrocodone is primarily used to modify pain signaling in the central nervous system through interaction with body's opioid receptors and since it is a prescription drug, remember that it is prescribed by doctors to those patients who are experiencing chronic pain and looking for relief.

PS. anxiety, fatigue, trouble sleeping/nightmares are mild side effects of the drug and symptoms generally abate when the dose wears off.

2. Clonazepam is given in panic disorder and for short-term management of anxiety and fatigue, insomnia, coordination and visual disturbances are documented ADR [adverse drug reaction] of the drug.

3. The body breaks down some medications for pain to get rid of them and St. John Wort might decrease how fast the body gets rid of some medications for pain, and by decreasing how fast the body gets rid of some medications for pain, St. John's wort might increase the effects and side effects of some medications for pain.[hydrocodone, oxycodone, morphine]

4. St. John's wort increases serotonin and so does some medications for depression also increase the brain chemical serotonin and taking St. John's wort FOR DEPRESSION along with these medicine(s) might increase serotonin too much and cause serious side effects including heart problems, shivering, and ANXIETY.

PS. check with your attending doctor/psychiatrist regarding possible drug interaction between the same.
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What Causes Fatigue While On Hydrocodone?

** Thanks for contacting with your health concern 1. Hydrocodone is primarily used to modify pain signaling in the central nervous system through interaction with body s opioid receptors and since it is a prescription drug, remember that it is prescribed by doctors to those patients who are experiencing chronic pain and looking for relief. PS. anxiety, fatigue, trouble sleeping/nightmares are mild side effects of the drug and symptoms generally abate when the dose wears off. 2. Clonazepam is given in panic disorder and for short-term management of anxiety and fatigue, insomnia, coordination and visual disturbances are documented ADR [adverse drug reaction] of the drug. 3. The body breaks down some medications for pain to get rid of them and St. John Wort might decrease how fast the body gets rid of some medications for pain, and by decreasing how fast the body gets rid of some medications for pain, St. John s wort might increase the effects and side effects of some medications for pain.[hydrocodone, oxycodone, morphine] 4. St. John s wort increases serotonin and so does some medications for depression also increase the brain chemical serotonin and taking St. John s wort FOR DEPRESSION along with these medicine(s) might increase serotonin too much and cause serious side effects including heart problems, shivering, and ANXIETY. PS. check with your attending doctor/psychiatrist regarding possible drug interaction between the same.