Thanks for your question on Health Care Magic. I can understand your concern. No need to worry much for the benign cyst in spleen. But follow up with ultrasound every six monthly fir 1st year is required to confirm the benign nature of lesion. If size and appearance of cyst remain same then it is benign cyst. But if size increases or cyst becomes more heterogeneous then you need biopsy from the lesion to rule out malignancy. Hope I have solved your query. I will be happy to help you further. Wish you good health. Thanks.