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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Took Antibiotics For Typhoid, Still Pain In Different Parts Of Abdomen, Weakness. IGM Positive. Recurrence ?

hi i am 28 years old .5 months back i suffered fever and typhidot IGG and IGM were positive. i took antibiotic and it became normal. but feel pain in different parts of abdomin and a lot of weakness , sometimes motions and lite fever. i again get tested , now typhidot IGM is positive and IGG is negative. Doctor gave only a tab for stomach and multivitamin. do i have to take antibiotic again ??
Tue, 8 Oct 2013
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General & Family Physician,  's  Response
IgM is an acute response to the infection while IgG antibody is an chronic response of infection. So when you are first tested for Typhoid and both the antibodies are positive suggestive of you had an acute infection which is becoming chronic that means your are having an infection which has not been treated and now its for a longer duration.
After you get treated for typhoid and tested showing IgM positive indicated a fresh infection with typhoid. Its not the same one as if its reccur it will show IgG antibodies instead of IgG as typhoid Ag is there in their memory. So now again you have to go for Typhoid treatment means follow the whole course again and take care of food as you have eaten contaminated food for the second time.
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Took Antibiotics For Typhoid, Still Pain In Different Parts Of Abdomen, Weakness. IGM Positive. Recurrence ?

IgM is an acute response to the infection while IgG antibody is an chronic response of infection. So when you are first tested for Typhoid and both the antibodies are positive suggestive of you had an acute infection which is becoming chronic that means your are having an infection which has not been treated and now its for a longer duration. After you get treated for typhoid and tested showing IgM positive indicated a fresh infection with typhoid. Its not the same one as if its reccur it will show IgG antibodies instead of IgG as typhoid Ag is there in their memory. So now again you have to go for Typhoid treatment means follow the whole course again and take care of food as you have eaten contaminated food for the second time.