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Dr. Andrew Rynne
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Dr. Andrew Rynne

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Exp 50 years

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Taking Lisinopril HCTZ For High BP. Have Leg Cramps, Anxiety, Panic Attacks And Increased Urination. Side Effects?

I was prescribed lisinopril hctz once a day for high blood pressure. Within a week I had severe leg cramps , facial tics, head twitches, panic attacks, heavy legs, anxiety, extremely increased urination (multiple times an hour). Went to doctor they denied it could be medication but changed me to just lisinopril. I am now having a lot of trouble sleeping, dizziness, occassional tics and cramps. Can this be lisinopril still? If I stop taking it how long will it take this to stop?
Thu, 14 Mar 2013
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Internal Medicine Specialist,  's  Response
Dear friend, welcome and thanks for entrusting your query here at Healthcaremagic!
I am Dr. Prasad Akole (Critical Care Expert- http://bit.ly/Dr-Prasad-Akole) and am glad to address to your query here.


Since you had increased urine amount due to the water pill (diuretic) HCTZ, you likely have developed severe electrolyte imbalance.
Low sodium (hyponatremia) is a common side-effect along with low potassium.
It can cause all these crazy sensations and sometimes drowsiness and later seizures (fits).

Please consult your doctor and check sodium and potassium levels.
Lisinopril may contribute little. You can take it till things are evaluated. Or switch to an ARB category of anti-hypertensives on doctor’s prescription.

Stop the HCTZ combination. The symptoms may take variable time of few days to normalize.


I hope to have answered your query satisfactorily. I would be glad to answer any further queries. Please ask for any clarifications before closing and rating this answer.
Take care and please keep me informed of your progress at http://bit.ly/Dr-Prasad-Akole
Good Luck! Thank you!!
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Taking Lisinopril HCTZ For High BP. Have Leg Cramps, Anxiety, Panic Attacks And Increased Urination. Side Effects?

Dear friend, welcome and thanks for entrusting your query here at Healthcaremagic! I am Dr. Prasad Akole (Critical Care Expert- http://bit.ly/Dr-Prasad-Akole) and am glad to address to your query here. Since you had increased urine amount due to the water pill (diuretic) HCTZ, you likely have developed severe electrolyte imbalance. Low sodium (hyponatremia) is a common side-effect along with low potassium. It can cause all these crazy sensations and sometimes drowsiness and later seizures (fits). Please consult your doctor and check sodium and potassium levels. Lisinopril may contribute little. You can take it till things are evaluated. Or switch to an ARB category of anti-hypertensives on doctor’s prescription. Stop the HCTZ combination. The symptoms may take variable time of few days to normalize. I hope to have answered your query satisfactorily. I would be glad to answer any further queries. Please ask for any clarifications before closing and rating this answer. Take care and please keep me informed of your progress at http://bit.ly/Dr-Prasad-Akole Good Luck! Thank you!!