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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Taken Gemzar And Cisplatin For Pancreatic Cancer. Orange Urine, Brown Stools. Recurrence?

I have had pancreatic cancer that spread to the liver. I have had treatment with gemzar and cisplantin along with tritium 90 spores sent to my liver by the femoral artery. I now have started to notice orange urine and my stools from my colostomy are of a light brown color. Is this a possible indication the cancer has re-occurred in my liver. Should I have a c19-9 lab test.
Sat, 29 Jun 2013
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General & Family Physician 's  Response
Hi,

Both cisplatin and Gemzar have a side effect of causing hemolysis. Hemolysis means the breakdown of RBC. The broken down RBC release hemoglobin which is broken down to iron and bilirubin. This bilirubin can cause the orange color urine and the brown stools that you are experiencing. The best course of action for you is to consult your oncologist again. If there is any other cause other than this, the oncologist will find it and then advise you better on the management. I hope this helps.

Dr Vineet
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  User's Response
Hi
The color change of urine and stool is because of chemotherapy, but still you should consult your oncologist for further evaluation. Have good day
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Taken Gemzar And Cisplatin For Pancreatic Cancer. Orange Urine, Brown Stools. Recurrence?

Hi, Both cisplatin and Gemzar have a side effect of causing hemolysis. Hemolysis means the breakdown of RBC. The broken down RBC release hemoglobin which is broken down to iron and bilirubin. This bilirubin can cause the orange color urine and the brown stools that you are experiencing. The best course of action for you is to consult your oncologist again. If there is any other cause other than this, the oncologist will find it and then advise you better on the management. I hope this helps. Dr Vineet