I have staph in nose. Took Bactrim two weeks and cellulitis started to come back. Last evening ENT put me on Clindomycin 300 mg. q 8 hours, but it's too often. I need a few more hours between doses. I want to try q 12 hrs. I have a LOT of trouble with mycins and cillins. I have IBS and had two colonectomies (due to doctor error in hysterectomy, not the IBS). I take 5 billion ?? of L. Reuteri (3 strains) daily. I know I can't do q 8 hours, but I feel better starting at 8 hours. I have read of others who took lesser amount or took it like I think I might handle it. I can't upset my ibs too much if I can avoid it.