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Suggest Treatment For Severe Allergy After Treated Low IGG Level
My 13 year old daughter was diagnosed with hypogammaglobulinaemia after her bloodwork showed that her igg and iga levels were slightly lower than normal. She had repeated upper respiratory infections. She had one ivig treatment and responded well so they removed her profalactic zithromax antibiotic. Her recent bloodwork showed almost normal levels of igg s but she still battles with severe allergies and frequently gets sick. How can I make it better for her. Is there something we are missing?
Wed, 6 Sep 2017
Hi,
Generally children with isolated IgA deficiency have allergic symptoms. But your duaghter has both IgG and IgA deficiency. Probably she has common variable immunodeficiency. Isolated IgA deficient children have allergic reaction to IVIg as well.
There is nothing specific which can be done to prevent allergies. Only solution is to avoid substances that cause allergy and also symptomatic treatment in the form of antihistaminics (such as cetrizine), when she gets allergic complaints.
She would need regular IVIg supplementation as well. I would also consider continuing antibiotic prophylaxis.
Hope I have answered your question. If you have any further questions I will be happy to help.
With regards,
Dr. Girish Kamat
Generally children with isolated IgA deficiency have allergic symptoms. But your duaghter has both IgG and IgA deficiency. Probably she has common variable immunodeficiency. Isolated IgA deficient children have allergic reaction to IVIg as well.
There is nothing specific which can be done to prevent allergies. Only solution is to avoid substances that cause allergy and also symptomatic treatment in the form of antihistaminics (such as cetrizine), when she gets allergic complaints.
She would need regular IVIg supplementation as well. I would also consider continuing antibiotic prophylaxis.
Hope I have answered your question. If you have any further questions I will be happy to help.
With regards,
Dr. Girish Kamat
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