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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Depression And Sleep Disorders

my husband takes cymbalta and has for more than 10 years. He also takes three different meds for high blood pressure and two different blood thinners. Is there significant drug interactions that would cause him to stop taking the cymbalta or at the very least switch to something else. His depression has returned and he is having sleep issues.
Mon, 24 Nov 2014
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Psychiatrist 's  Response
Hi.

I understand your concern .

Cymbalta contains duloxetine and it is one of the good medicines for depression.

If you are taking anti hypertensive medicine then need to do proper evaluation of class of that medicines . There are interaction with duloxetine but still it is safe to take it under observations .

SSRI sertraline / escitalopram are safely used in hypertensive patients.

Sertraline is the safest among all in cardio vascular compromised patients .

Lorazepam is safest benzodiazapine for sleep problems.

You can discuss all these options with your treating doctor .

Still if you have a query then feel free to ask .

Thank you .
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Suggest Treatment For Depression And Sleep Disorders

Hi. I understand your concern . Cymbalta contains duloxetine and it is one of the good medicines for depression. If you are taking anti hypertensive medicine then need to do proper evaluation of class of that medicines . There are interaction with duloxetine but still it is safe to take it under observations . SSRI sertraline / escitalopram are safely used in hypertensive patients. Sertraline is the safest among all in cardio vascular compromised patients . Lorazepam is safest benzodiazapine for sleep problems. You can discuss all these options with your treating doctor . Still if you have a query then feel free to ask . Thank you .