Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
189 Doctors are Online

Positive PPD result. Started with isoniazid. Suggest?

hi,im cheryl, i had my ppd test result 9mm and the nurse said it was positive,so they required me to have a blood test ,it turns out to be positive,so they asked me to have an x-ray .it turns out to be negative,but anyway i started to take isoniazid ,the dr. recommends it.after 5months of taking those pills ,the clinic called that i needed to have a bloodtest again because they might get the wrong result during those days when i got tested,we were 30 patients,some turn out to be still positive while others including me turns out to be question is that.does the second result turns to be negative because i was almost finished my 6months medication?or i was really negative from the very beginning.also i heard that positive ppd should be 10-12mm.but in my case ive got only 9mm but the nurse who measure it says its positive?
Asked On : Sat, 2 Mar 2013
Answers:  1 Views:  329
Report Abuse
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Diseases and Conditions
Lab Tests
General & Family Physician 's  Response
Dec 2012
Hello Charlyn,

Thanks for posting on HCM,

Positive mantous test or PPD does not directly mean that you have an active TB infection. It could mean that you were ones exposed to TB but did not develop the diseases. Normally most immunocompetent people are PPD positive especially in high TB endemic regions. They are also false positive, true positive, false positive and true negative test results. These are determined by the size of the PPD and in your case, you probably had a false positive result (which signifies you are negative).
More over, the decision to place you on antiTB drug ( like isoniazid) should have been complemented with some clinical signs like presence of a pulmonary infection, lymphadenitis, POTs diseases and other signs that they might be a chronic infection that requires TB remedy. If you were not manifesting any signs of active TB (like night sweats, intermittent fever especially at night, signs of infection etc) then the decision to place on isoniazid based on positive PPD is wrongly justified.
Well after completing the treatment of TB, PPD could still come positive but active TB infection has been eradicated, therefore we still come to the point that taking isoniazid and evaluating directly with PPD is not properly justified. The only direct test is determining the presence of acid-fast-bacilli (AFB) myobacterium in either sputum, biopsy of a mass or lymph node etc.
I sincerely wish you the best
Dr Nsah
Answered: Mon, 4 Mar 2013
I find this answer helpful

4 Doctors agree with this answer

Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]


Loading Online Doctors....
© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor