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Low platelets count, liver spleen enlarged, TORCH, VDRL, BCR, ABL negative

My daughter is having some issues in blood...low platelates count since birth... liver splen enlarged.. 2 times bone marrow done, nothing found...Haematological teats for acute leukamea and BCR/ ABL done...both negative....TORCH, VDRL also negative.kindly help Now she is 1 year old, platelates counts are 2 lacs...but liver and spleen are still enlarged...What should be my next step. Kindly revert at YYYY@YYYY
Asked On : Sat, 5 May 2012
Answers:  1 Views:  136
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  User's Response
I can understand your concern regarding these negative tests.
However, only a careful systematic approach will ensure that nothing is missed out.
Presently, peripheral blood and bone marrow cell morphology need to be done, if they've not been done already. The platelets and their bone marrow precursors need to be carefully assessed, so as to understand what exactly is responsible for the low counts. Since you said the count has been so since birth, we may be dealing with a congenital platelet disorder, but the tests you mentioned are insufficient to unravel which one it is.
You should see a specialist hematologist, to help you through the process.
Best regards.
Answered: Mon, 4 Jun 2012
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