hello my wife 57yr old suffering multipalmailoma since 30 months as diagonosed. she had put on thalidomide 110 mg cap od along with dexamethasine 8mg but patient could not respond adn platlat gone down to80000per cumm with five days of taking the medicene .it stoped and after one month lenolidamide10mg along with decmax 20mg started but patient not again responded and stopped .now tab melphalm 5mg bd along with tab prednisolone 40mg bd 4day in amonth started since last four month but patient feel very uncomfertable .i have seen on net that there is no solution of the multipalmama and not curable life span on threat 24month to 64 month. please advise .