I have been asked to take dupheston tablet twice a day. Is it safte to take it. Why have I been asked to take this medicine. My 6th month has started. I read few articlesw in the internet. Should I continute to take it or not. I am taking fol 5, Calciteron, Pink M-Iron.
It contains dydrogesterone which is progesterone, However progesterone is not approved for use during pregnancy in any advanced country such as US, UK etc. Some authorities in the past used to recommend its use in recurrent miscarriage or threatened abortion but now there is now no evidence of any benefit from such practice and recommend against the use in early pregnancy unless there is proven deficiency.
One problem with this medicine is that female baby may suffer from hirsutism (unwanted hair on face, chest etc). Therefore if at all progesterones have to be given when there is documented deficiency, it is preferable to give dydrogesterone (sold as Duphaston which your doctor has prescribed to you) or medroxyprogesterone (sold as Meprate).
I think you might have previous abortion and this could be reason for prescribing this drug. If benefits outweigh the risks then it is good to take and your doctor is best person to decide this. Many obstetricians still prescribe this drug and it has not caused any significant effect on baby.
Regards Dr Santosh Dr Santosh
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Is Duphaston Safe During Pregnancy?
Hi and welcome to HCM It contains dydrogesterone which is progesterone, However progesterone is not approved for use during pregnancy in any advanced country such as US, UK etc. Some authorities in the past used to recommend its use in recurrent miscarriage or threatened abortion but now there is now no evidence of any benefit from such practice and recommend against the use in early pregnancy unless there is proven deficiency. One problem with this medicine is that female baby may suffer from hirsutism (unwanted hair on face, chest etc). Therefore if at all progesterones have to be given when there is documented deficiency, it is preferable to give dydrogesterone (sold as Duphaston which your doctor has prescribed to you) or medroxyprogesterone (sold as Meprate). I think you might have previous abortion and this could be reason for prescribing this drug. If benefits outweigh the risks then it is good to take and your doctor is best person to decide this. Many obstetricians still prescribe this drug and it has not caused any significant effect on baby. Regards Dr Santosh Dr Santosh