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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Do Monoclonal Antibodies Help In Cancer Therapy?

Hello Doc,
My name is Rana. I am doing a biology research in school about monoclonal antibodies, and I was hoping you can help me in it if you can. my questions are :
How monoclonal antibodies can help in cancer therapy? and how does this therapy work?
Since when this therapy had been used and how many people improved or were cured because of it?
Thank you
Wed, 21 Jan 2015
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Oncologist, Surgical 's  Response
Hi Rana. All cells in the body have a large number of receptors present on the surface and inside the cell. These are necessary for their normal functioning. Cancer cells utilise some of these receptors to enhance their growth and stay immortal. So we as oncologists have started to use these receptors for treating cancer by blocking these receptors. That is done by using monoclonal antibodies and is called targeted therapy. It was started in the 90s with a drug called imatinib. Now there is a plethora of such drugs available and are used in a variety of cancers and are working wonders.
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How Do Monoclonal Antibodies Help In Cancer Therapy?

Hi Rana. All cells in the body have a large number of receptors present on the surface and inside the cell. These are necessary for their normal functioning. Cancer cells utilise some of these receptors to enhance their growth and stay immortal. So we as oncologists have started to use these receptors for treating cancer by blocking these receptors. That is done by using monoclonal antibodies and is called targeted therapy. It was started in the 90s with a drug called imatinib. Now there is a plethora of such drugs available and are used in a variety of cancers and are working wonders.