Hello there! Thank you for asking. Here are some treatment modalities you can pick from, Remember parkinsons and RLS excacerbates each other. So be watchful and compliant in your medication with a constant touch to neurologist and GP Here is the treatment option list. A-Antiparkinson Agents, Dopamine Agonists Pramipexole (Mirapex, Mirapex ER) Ropinirole (Requip, Requip XL) Levodopa with carbidopa (Sinemet, Parcopa) Bromocriptine mesylate (Parlodel, Cycloset) Rotigotine (Neupro) B-Anxiolytics, Benzodiazepines Clonazepam (Klonopin) C-Opioid Analgesics Low Potency( codein) High potency if refractory to low one.( oxycodone hydrochloride, methadone hydrochloride, and levorphanol tartrate) care for addiction. D-Anticonvulsants, Other Gabapentin Enacarbil (Horizant) Gabapentin (Neurontin) Pregabalin (Lyrica) E-Alpha2-Adrenergic Agonists Clonidine hydrochloride (Catapres, Kapvay, Nexiclon XR) F-Iron Salt Iron sucrose (Venofer) take 325mg iron 60 mins before meal with 250 mg Vitamin C supplements. G- Herbal Remedy -Yokukansan Anecdotal evidence from Japan suggests that yokukansan (an herbal remedy) is effective in the treatment of RLS H-Oral corticosteroids Deltacortil (prednisone) But you need a close monitoring by your Neurologist for RLS. Mean while see the Psychiatrist for Depressive sympoms. Sign up to Group therapies, vocational and recreational therapies. And I am sure you will feel better. Take care regards Dr S Khan