Hello ethco6 thanks for your question First of all I would like to tell you that the episacral lipomas has nothing to do with the muscle spasms, they are very less likely to cause such type of symptoms. You are having such type of spasms for last 4 years and I assume investigations are alright. Fibromyalgia or it is also called as Chronic Fatigue Syndrome is a chronic disorder that is usually characterized by multiple muscle aches, spasms, sore throat, anxiety and many other non specific symptoms. So we can keep fibromyalgia as one possibility. Other possible causes may be Vitamin B12 deficiency, which may also cause chronic fatigue. Iron deficiency is also a possibility. Kindly get your investigations done for Vit B12, iron, and calcium. If every thing comes normal only then fibromyalgia is only possibility. Treatment if fibromyalgia is mainly directed to symptomatic relief. NSAID drugs as Brufen, Aspirin are useful. Other drugs groups like SNRIs as Milnacipran, Duloxetine are drug of choice for illness. Pregabalin is also used to improve nerve muscle condition so please continue taking it. there is no harm to give a trial to this group of medication directed towards treatment of fibromyalgia. thanks hope I cleared your doubt. take care.