Hi there ~
I understand your concerns. You have a problem with dependence on many drugs. I believe that you are also having problems with side effects from long term use including gastrointestinal ones, that need to be carefully looked into. Although you do not give me a complete history above, I recommend that you visit with a psychiatrist
who can take a complete history and do a physical examination, run lab tests as well as recommend any imaging studies that are required to get rid of the physical problem. You definitely need rehabilitation
treatment while you are going off of the substances that you are using and this needs to be done under supervision of a qualified psychiatrist. I wish you the very best in recovery.
I hope this helps. Take care and have a lovely day!