Hi,thanks for writing to HCM. All the findings in your description suggest a degenerated lumbar spine. The only lesion that is a matter of concern is the Listhesis of L5 over S1. In obese patients this lesion progresses to Grade 2 & 3 very quickly and leads to significant neural elements compression. I suggest you the following measures * Try to cut down your body weight if your are obese * Never try to lean or bend forwards to pick up things from the floor * use a lumbosacral corset to support your spine so as to prevent further listhesis * physiotherapy to strengthen the back muscles. Despite the above measures, If your listhesis is progressing (confirmed by serial xrays) or if you develop radiating pain with tingling & numbness down into the leg, you may need surgical intervention (posterior spinal fixation with fusion). Hope this helps