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Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does benadryl cause increase in SGPT (ALT) level?

Hello Female 57. My SGPT (ALT) was at 17 one month ago. Recently, 30 days later, my level increased to 24. I took benadryl (2x 25mg) at that exact day I had the blood panel. Before that never took benadryl before. Could the benadryl cause the increase from 17 - 24? Thank you.
Wed, 25 Sep 2019
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Addiction Medicine Specialist 's  Response

17 and 24 are generally within the normal range and that is a small change that often occurs without there being an actual abnormality. If the result is far outside the normal range for that lab, then it would have to b evaluated.

The ALT alone being elevated generally is from alcohol acute effect or another direct liver toxin. And generally this is a rapidly reversible issue when the drug is stopped.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Dr Matt Wachsman, Addiction Medicine Specialist
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