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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does An Oncologist Need To Look At CA-125 And CEA Results?

I am a 10-year breast cancer survivor (diagnosed at 44) whose internist has been monitoring CA-125. A year ago it was 19 measured on the bayer Advia Centaur assay; this year it is 31.6 measured on the Roche Eclia assay. CEA, measured with the same assays, is also up from 1.4 to 2. Is this cause for concern? Do I need to schedule an ultrasound or go back to my oncologist with this information?
Wed, 25 Apr 2018
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Pathologist and Microbiologist,  's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

CA-125 levels are normal up to 35 units/mL and CEA levels up to 3ng/mL is normal. Your both CA-125 and CEA levels are normal. No need to worry at this point of time. But, requires close follow-up.

My suggestion is repeat the test after 3 or 6 months. These levels are for ovarian status. Is there any family history of breast or ovarain cancer?

What about the BRCA1 and BRCA2 status? If you want more suggestions, consult oncologist.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Siddartha
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Does An Oncologist Need To Look At CA-125 And CEA Results?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. CA-125 levels are normal up to 35 units/mL and CEA levels up to 3ng/mL is normal. Your both CA-125 and CEA levels are normal. No need to worry at this point of time. But, requires close follow-up. My suggestion is repeat the test after 3 or 6 months. These levels are for ovarian status. Is there any family history of breast or ovarain cancer? What about the BRCA1 and BRCA2 status? If you want more suggestions, consult oncologist. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Siddartha