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Diagnosed with carcinoma nasopharyngealis type nonkeratinising. Why do I have this?

I am from Europe, Albania and I have Dg. The conclusion: The material received is part tissue membrane out with a nodular changes on one side. Microscopically observed surface partly epitel plakor and partly epitel pseudostratifikuar, in a part of become so ulcerated tissue beneath Tumoural built by groups of islands, ribbons and some trabekula atypical polygonal epithelial cells or some axle, set in stromen fibrotic infiltrates numerous limfoplazmocitare. Unnoticed and glands of the mucous membranes packages coated with regular epitel. Dg: Carcinoma nasopharyngealis-type nonkeratinising , Differential, G 2 ICD-O 8072/3 I am not Chinese, nether African why I have this ?
Asked On : Fri, 31 Aug 2012
Answers:  2 Views:  25
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Pathologist and Microbiologist 's  Response
welcome to HCM!
Yes,nasopharyngeal carcinoma is more common in certain regions of South east Asia and Africa than elsewhere but the etiology of NPC seems to follow a multi-step process, in which EBV, ethnic background, and environmental carcinogens all seem to play an important role. EBV DNA levels may sometimes correlate with treatment response and may predict disease recurrence,
Other causative factors include genetic susceptibility, consumption of food (in particular salted fish)containing carcinogenic volatile nitrosamines.
Your biopsy report says nonkeratinising G2 TYPE this nonkeratinizing undifferentiated form also known as lymphoepithelioma is most common, and is most strongly associated with Epstein-Barr virus infection .
Hope I have answered your query!take care!
Answered: Sat, 21 Sep 2013
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Oncologist, Surgical Dr. Pranjal Kulshreshtha's  Response
This type of cancer can occur in any person in the world, any race, country, caste, color, creed, religion, habitus. Of course, there are certain nationalities that have a predisposition to development of this cancer due to genetic or environmental reasons. But it can occur in any person even without a predisposing factor. People who smoke or take alcohol are also predisposed. Even passive smoking can cause this cancer. If you have any of these addictions then you have your answer. Even otherwise, as i mentioned, anyone can have it.It is a completely curable kind in most cases and the treatment includes radiation therapy to the affected part and neck
Answered: Sat, 21 Sep 2013
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