during or after I.V. fluids is well known. These type of reactions are common with some drugs and also with blood. Before giving this drug- Rituxon usually they will give premedication
. this premedication will prevent the development of chills and rigors. some times rapid inflow of the drug can cause these things. Stopping of the infusion for some time and restart can be
done. One thing you should remember: whenever you feel these symptoms , immediately inform the medical attendant- nurse, or doctor. and you should not worry for this. as this is common with some drugs such as Rituxon.