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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Woman With Resistant Ovarian Failure Conceive?

a female 27yrs of age with primary amenorrhoea.USG abdomen revealed hypoplastic/infantile uterus wid small ovaries.hormonal study shows FSH raised 18times and LH raised 8times..she got withdrawal bleeding after medication but after that again failed to get her periods..was diagnosed as ?resistant ovarian failure..she has normal development of secondary sexual organs.karyotype normal female 46XX.IS THERE ANY WAY SHE CAN CONCEIVE..
Mon, 27 Feb 2017
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OBGYN 's  Response
Hi ,
How are you doing ?
With IVF she still has a chance.
High levels of FSH , suggest that her ovaries are not functioning . But as she did have a uterus on scan & very luckily as she had withdrawal bleeding on hormones( suggesting that the inner lining of uterus is healthy when on hormones. So that would mean that the uterus can be prepared.
So she will need a good course of cyclical Higher dose Combined hormone pills for 6-8 mths. This will prepare the muscles of uterus , which looked hypoplastic on scan. ( if not prepared she will be prone for uterine rupture , preterm labor.). Once the lining of the uterus is good enough & uterine muscles are healthy, she is ready for IVF.
Donor eggs can be taken, each of them injected with husband's sperm & embryos frozen. When the inner lining of the uterus is adequate for the cycle( using selective estrogen hormone), the embryos can be kept. She can have babies as long as the embryos are frozen.
She will need a cervical cerclage stitch once at 16 weeks, good supplementation of progestrone hormone through out pregnancy.
Now she also needs good calcium & iron supplementation & an eye on the cholesterol level.
Hope I have clarified your query
Do write back if any more queries
All the best
Dr.Balakrishnan
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Can Woman With Resistant Ovarian Failure Conceive?

Hi , How are you doing ? With IVF she still has a chance. High levels of FSH , suggest that her ovaries are not functioning . But as she did have a uterus on scan & very luckily as she had withdrawal bleeding on hormones( suggesting that the inner lining of uterus is healthy when on hormones. So that would mean that the uterus can be prepared. So she will need a good course of cyclical Higher dose Combined hormone pills for 6-8 mths. This will prepare the muscles of uterus , which looked hypoplastic on scan. ( if not prepared she will be prone for uterine rupture , preterm labor.). Once the lining of the uterus is good enough & uterine muscles are healthy, she is ready for IVF. Donor eggs can be taken, each of them injected with husband s sperm & embryos frozen. When the inner lining of the uterus is adequate for the cycle( using selective estrogen hormone), the embryos can be kept. She can have babies as long as the embryos are frozen. She will need a cervical cerclage stitch once at 16 weeks, good supplementation of progestrone hormone through out pregnancy. Now she also needs good calcium & iron supplementation & an eye on the cholesterol level. Hope I have clarified your query Do write back if any more queries All the best Dr.Balakrishnan