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Can Overdose Of Tylenol Cause Any Harm In Pregnancy ?
I am 16 weeks pregnant and have been getting horrible migraines. My doctor said Tylenol is fine to take, but tonight I took two extra strength Tylenol and then took a second dose three and a half hours later by accident. Should I be worried about overdosing? Altogether I have take six extra strength Tylenols today
Wed, 13 Nov 2019
Hi,
Yes. Acetaminophen (APAP) is the most common drug overdose in pregnancy. APAP has been demonstrated to cross the placenta and in toxic doses may harm the fetal and maternal hepatocytes. Fetal hepatocytes metabolize APAP into both active and toxic metabolites. These toxic metabolites may cause fetal hepatic necrosis.
Hope I have answered your query. Let me know if I can assist you further.
Regards,
Dr. Ajeet Singh, General & Family Physician
Yes. Acetaminophen (APAP) is the most common drug overdose in pregnancy. APAP has been demonstrated to cross the placenta and in toxic doses may harm the fetal and maternal hepatocytes. Fetal hepatocytes metabolize APAP into both active and toxic metabolites. These toxic metabolites may cause fetal hepatic necrosis.
Hope I have answered your query. Let me know if I can assist you further.
Regards,
Dr. Ajeet Singh, General & Family Physician
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