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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Zoladex Shots Reduce The Chances Of Breast Cancer And Its Dosage?

I got a Skin Sparing Mastectomy done on my right breast on March 30th, 2011 as the tumour was malignant. Post that i completed my 8 cycles of Dose-Dense Chemotherapy followed by 28 fractions of radiation therapy. My ER & PR are 90% positive & hence now i am on hormone therapy taking 1x20mg tablet of Tamoxifen daily & will have to do so for the next 5 years. I have attached my post surgical report. My Onco yesterday also advised that i get Injection Zoladex for 2 years (@ 3.6 mg monthly or 10.8 mg quarterly). I am 36 years unmarried. I do understand that zoladex will suppress the function of the ovaries for 2 years. My ques: 1) By how much does Zoladex reduce chances of recurrence when taken with tamoxifen in comparison to only Tamoxifen ? 2) Basis my report is it advisable to get Zoladex shots ? and why is 2 years considered ideal & not less or more ?
Mon, 3 Aug 2020
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General & Family Physician 's  Response
Hello,

Zoladex is used subcutaneously to suppress the growth of certain cancerous cells by controlling the hormone levels in the body, especially in breast cancers. As you have already undergone surgical, chemo and radiation therapy. Your doctor has suggested this to control the growth of cancerous cells in the body.

As it is suggested by your doctor considering its efficacy and maximum benefits for you, with regular follow ups only the progress of the therapy can be understood. The duration of the therapy varies patient to patient and the overall condition of the patient. So your doctor will be able to guide you best on this as he is well aware of your medical history over the years.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Manisha Auradkar, General & Family Physician
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Can Zoladex Shots Reduce The Chances Of Breast Cancer And Its Dosage?

Hello, Zoladex is used subcutaneously to suppress the growth of certain cancerous cells by controlling the hormone levels in the body, especially in breast cancers. As you have already undergone surgical, chemo and radiation therapy. Your doctor has suggested this to control the growth of cancerous cells in the body. As it is suggested by your doctor considering its efficacy and maximum benefits for you, with regular follow ups only the progress of the therapy can be understood. The duration of the therapy varies patient to patient and the overall condition of the patient. So your doctor will be able to guide you best on this as he is well aware of your medical history over the years. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Manisha Auradkar, General & Family Physician