Hello As you mentioned that you were taking methotraxate for February 2014 i.e. almost you are taking this drug for eczema for 10 months . No doubt this drug sometimes causes anaphylaxis , but also produces bone marrow depression ( this may be the cause of severe dizziness ). As you mentioned that EKG, blood , urine , blood pressure and C T scan , all are normal ,so such symptoms may be due to these possibilities ,these include. 1 Hypotension , as I have noted that whenever some patient wake up in the morning suddenly blood pressure falls and there develop dizziness . But after sometimes patient recover and blood pressure elevated and reached at normal level , so this may be in your case. 2 Hyper acidity may be the another reason . Methotraxate also causes hyper acidity , so be careful about that also . Because in hyper acidity , doctor will not find any abnormality in routine examination. 3 Tension or anxiety may be the another reason of such symptoms. 4 While sever allergic reaction may be the cause of such symptoms . In my opinion , consult a doctor and get blood pressure for three consecutive days. However, there are so many other reasons , like Minere s disease , but consult a physician and get his opinion.