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Why Would One Experience An Upset Stomach About A Month After Having Undergone Bilateral Knee Replacement?

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Posted on Fri, 3 May 2024
Question: Dear Sir/Madam

My Mother Has undergone Bilateral Knee replacement on 30th March 2018 its 26 days over now.She would be feeling Stomach upset from 5-7 days if she eats anything hard she would be having Gas and will not feel comfortable and she is getting more hiccups.



Could you please let us know if any additional test needs to be performed to rule out the problem.?



Currently she is on following medications

Sompraz D 1 - 0 -0 before food

TAB PREGABA 1-0-0 AFTER FOOD FOR PAIN

TAB GEMER P2 1-0-1 BEFOORE FOOD FOR SUGAR
doctor
Answered by Dr. Ramesh Kumar (3 hours later)
Brief Answer:
Gut flora depletion.

Detailed Answer:
Hello and thanks for query my dear,
Our gut consist of colonies of bacterias which are responsible for proper digestion of food.If this microbiota is disturbed food is improperly fermented causing production of large amount of gases in gut leading to bloating or belching.These gases may compress diaphragm causing hiccups.In old patient mobility of intestines is severly compromised leading to accumulation of large amount of gases in intestines.As persitaltic moments are week gas accumulates in intestines.
Another condition is-
Small Intestinal Bacterial Overgrowth can be a reason of severe flatulence .
Small intestinal bacterial overgrowth (SIBO) refers to a condition in which abnormally large numbers of bacteria are present in the small intestine, and the types of bacteria in the small intestine resemble more the bacteria of the colon than the small intestines causing improper and disturbed food digestion.

I would suggest her to go for few tests
Ultra sound abdomen
Stool test under microscope
Complete blood count
Total and differential leucocyte count.

If stool test is positive for bacterial or protozoal infection.Start taking Zithromax(Azithromycin 500 mg once daily) and secnidazole 1 gram daily for 5 days.
Along with it take Fybrogel husk,It will increase the bulk of your stools.

Start giving her probiotic daily for 10 days.Probiotics are live bacteria and yeasts that are good for your health, especially yourdigestive system. We usually think of bacteria as something that causes diseases. But your body is full of bacteria, both good and bad. Probiotics are often called "good" or "helpful" bacteria because they help keep your gut healthy.
For hiccups Baclofen 10 mg can be given as and when required.
General precautions-
Eat light and easily digestible food.
Avoid meat.
Try boiled food(Vegetables) with spices and herbs for a week.
Drink plenty of orange juice and coconut water.

Hope i answered your query well.
Follow up with reports.
Regards.
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Ramesh Kumar (3 hours later)
Thanks for useful information.As suggested by You we have done following test attached the report for the same.Request you to review the reports and provide the feedback.

Ultra sound abdomen
Complete blood count
Total and differential leucocyte count.

We will do Stool test tomorrow and share the results tomorrow.

As suggested by you to start giving her probiotic daily for 10 days.My mother is diabetic can you please suggest some diabetic Friendly probiotic Foods/Medicines which can be taken ?

Also could you please suggest Light and easily digestible food for Diabetics which can be taken.

doctor
Answered by Dr. Ramesh Kumar (48 minutes later)
Brief Answer:
Follow up answer.

Detailed Answer:
Hello and thanks for follow up sir,
She has got pus cells in her urine and her fasting blood sugar is also high.Sugar always acts as a culture media for various bacterias and fungus.
So initially i would like to add
Tab Trazanta 5mg once daily 9a.m to contol her blood sugar
plus an antibiotic like Cefixime 400mg twice daily should be given for 5 days to control ongoing infection.
USG shows mild fatty liver changes(age related).

Give her 2 scoobs of veg protein(sugar free) with one cup of fat free milk.This would take care of her daily protein requirement and would keep her satiety suppressed.
Some other foods are
Bhuna chana
Peanuts
10gram almonds
All green vegetables
Apple,guava,Strawberry,pear.
Rice flakes,churma etc
give her VSL#3named probiotic twice daily(a good one).

Thanks

Above answer was peer-reviewed by : Dr. Kampana
doctor
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Follow up: Dr. Ramesh Kumar (5 hours later)
We are already taking medications Gemepr P 2 Morning and Night after food.
My mother is having diabetes from past 8 years fir which she is already taking medication for that so wanted to check if additional medicine mention by you should be taken or existing medications would be enough.

Will take Cefixime 400mg as suggested by you.But wanted to check if it is having any side effects or interaction with any drugs which my mother is taking currently following medication

Also we will take VSL#3 as suggested by you just wanted to confirm if this is same for Daibetes.

Thanks for your help in advance
doctor
Answered by Dr. Ramesh Kumar (17 hours later)
Brief Answer:
All drugs are effective and safe.

Detailed Answer:
Hello dear and thanks for follow up,
Linagliptin belongs to the group of diabetes medications called DPP-4 inhibitors. It works by increasing the amount of incretin released by the intestine. Incretin is a hormone that raises insulin levels when blood sugar is high (especially after a meal) and decreases the amount of sugar made by the body.Its a very good drug and often used in patient in which metformin or glimipiride can't control sugar well.
Very safe in old patients and excellent results.

See she has infection in urine and has to take a good antibiotic for 5 days.Cefixime is among the safest cephalosporins very widely used and highly effective.No interaction with drugs she is on. don't consider nausea headache allergy etc as a side effect(even pollen can give you these symptoms).Don't unnecesarily google too much.
VSL#3 is one of the best imported probiotics and is very effective and well tolerated.Its sugar free,

Hope it cleared your query sir,
Please feel free to follow up any time.
Regards.
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Ramesh Kumar (28 hours later)
Dear Sir,
We have repeated Urine Routine once again in different Lab there it Shows Pus cells are normal attached the results for the same.Not sure why the variation in the results.Wanted to confirm if test results would depend at the time when we give Urine?
Do we need to still Continue Antibiotic since yesterday results does not show Pus cells in Urine.
Also attached the Stool Test results Request you to review and provide your inputs on the same.
Also when we consulted Gastrologist doctor they suggested to do following test
HTTG -DGP
S B12
S- NA+
ALT
Wanted to confirm if these test are required what can be determined by this?

Also doctor suggested to take following tablets Veloz 20 and Liofen 10 MG but i'm not sure why these tablets were given.Could you please let me know if this can be taken?

Im not getting VSl3 in medical shop could you please tell me the Correct name ?
doctor
Answered by Dr. Ramesh Kumar (25 minutes later)
Brief Answer:
Follow up answer.

Detailed Answer:
Wanted to confirm if test results would depend at the time when we give Urine?-No it does not. However it depends on quality of technician and machines a particular lab is having.

Do we need to still Continue Antibiotic since yesterday results does not show Pus cells in Urine-To be on safe side 4 tablets of cefixime are not going to cause any harm to her.So in case of deliema i would consider her as pus cell positive but give her cefixime for 3 days only.

Also attached the Stool Test results Request you to review and provide your inputs on the same-Pus cells are there in her stools.Whenever we are infected our body try to defend us but when immunity of body fails to kill external bacterias pus is formed.So again Cefixime has to be given for 3 days with metronidazole(anti protozoan)400mg thrice daily for 3 to 5 days.

HTTG -DGP-To rule out inflammatory bowel disease.I won't recomend it right now because she has a very short history plus her stool test shows infection.

B12-Vitamin B12 level-Not of much significance again.
Serum Sodium-Don't know whats the significance of just checking sodium levels in her case.

ALT is a part of liver function test.
Its a probitic named VSL#3 Can even get it online in USA.
Veloz 20 is an antacid and would help her with gas issues there is no harm in taking it.
Liofen 10 MG Tablet is an Antispastic agent which is used to relieve pain and improves the muscle movement.Can give both of them no problem,Would help her symptomatically.
Thank you.

Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Ramesh Kumar (2 hours later)
Sure will Give cefixime for 3 days as suggested by you.We are taking Mahacef 200mg
Thanks for reviewing Stool Test .
So Tab cefixime ( Mahacef 200mg) should be taken for 5 days along with metronidazole(anti protozoan)400mg ?

So as per as history we would be giving Following medication

cefixime for 5 days 1 -0 -1 after food
metronidazole(anti protozoan) for 5 days after food 1-1-1
Veloz 20 for acidity before Breakfast 1-0-1
VSL 3

Please revie it and let ne know if anything needs to be added or deleted
doctor
Answered by Dr. Ramesh Kumar (10 minutes later)
Brief Answer:
follow up.

Detailed Answer:
Hello again,
No mahacef is not a good one(MANKIND) company please use Taxim o or Zofix.
In case you can't get VSL#3 ask pharamcist to give any good quality probiotic.
Is Mahacef is available in USA?
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Ramesh Kumar (2 hours later)
Im from XXXXXXX they had given me Mahacef when i asked cefixime . I have given it for my mom Two days now but only at night.Is it safe to change to axim o or Zofix.?

Also wanted to check if this Bacteria infection will have any impact on Knee replacement recovery.
Please let us know taking Medicines mentioned above for 5 days would stop Infection? or anything needs to be done in Diet to control

Also can you please let us know if we can stop Taking Somparz D and start taking Veloz 20 only for one day before food?

axim o or Zofix 200mg would be enough?

Apart from previous medication was having clarification related to metronidazole(anti protozoan) whether it is injection or Tablet.How many mg/ml should be taken.Please give some name for that tablet that contains metronidazole(anti protozoan)

is this fine?
Metronidazole B Braun 500 mg/100 ml

Thanks for your help in advance
doctor
Answered by Dr. Ramesh Kumar (21 hours later)
Brief Answer:
Please take the antibiotic in doses and frequency suggested.

Detailed Answer:
Hello again my dear,

Giving antibiotic only at night would just cause antibiotic resistance. Period of action of cefixime is 12 hours. So antibiotics would kill bacterias for 12 hours but if you don't give the second dose for the next 12 hours those bacterias would again form their colonies.

Taxim 200 twice daily will be ok however 400 mg twice daily could be given initially for 3 days followed by 200 mg twice daily for 2 days.
Yes, you may stop Sompraz and start the other one.

Metronidazole (Metrogyl/Flagyl) tablet 400 mg thrice daily for 3 days followed by twice daily for 2 days.

Please don't alter doses of antibiotics on your own as this may lead to antibiotic resistance.
Hope I cleared your doubts.
Feel free to follow up.

Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
Answered by
Dr.
Dr. Ramesh Kumar

Gastroenterologist

Practicing since :1986

Answered : 2906 Questions

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Why Would One Experience An Upset Stomach About A Month After Having Undergone Bilateral Knee Replacement?

Brief Answer: Gut flora depletion. Detailed Answer: Hello and thanks for query my dear, Our gut consist of colonies of bacterias which are responsible for proper digestion of food.If this microbiota is disturbed food is improperly fermented causing production of large amount of gases in gut leading to bloating or belching.These gases may compress diaphragm causing hiccups.In old patient mobility of intestines is severly compromised leading to accumulation of large amount of gases in intestines.As persitaltic moments are week gas accumulates in intestines. Another condition is- Small Intestinal Bacterial Overgrowth can be a reason of severe flatulence . Small intestinal bacterial overgrowth (SIBO) refers to a condition in which abnormally large numbers of bacteria are present in the small intestine, and the types of bacteria in the small intestine resemble more the bacteria of the colon than the small intestines causing improper and disturbed food digestion. I would suggest her to go for few tests Ultra sound abdomen Stool test under microscope Complete blood count Total and differential leucocyte count. If stool test is positive for bacterial or protozoal infection.Start taking Zithromax(Azithromycin 500 mg once daily) and secnidazole 1 gram daily for 5 days. Along with it take Fybrogel husk,It will increase the bulk of your stools. Start giving her probiotic daily for 10 days.Probiotics are live bacteria and yeasts that are good for your health, especially yourdigestive system. We usually think of bacteria as something that causes diseases. But your body is full of bacteria, both good and bad. Probiotics are often called "good" or "helpful" bacteria because they help keep your gut healthy. For hiccups Baclofen 10 mg can be given as and when required. General precautions- Eat light and easily digestible food. Avoid meat. Try boiled food(Vegetables) with spices and herbs for a week. Drink plenty of orange juice and coconut water. Hope i answered your query well. Follow up with reports. Regards.