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What Does Papillary Carcinoma Of Thyroid Report Indicate?

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Posted on Mon, 9 Jun 2014
Question: Hello

I would like some assistance please. It may seem I am asking lots of different drs questions right now but a lot is going on. I have a left side lobectomy on April 29th 2014 followed by the left on May 5th . I have just met with my surgeon and the Path report says 1) Papillary Carcinoma (.5 cm ) and 2) Nodular hyperlasia with previous biopsy site changes


Specimen size : 4.5 x 3 x 1.4 cm
Tumor Focality ; Single Focus
Tumor size 0.5cm
Histolgic Type: Papillary Carcinoma
Variant: Onocytic
Architecture : Classical ( Papillary )
Cytomorphology : Oncocytic

Margins : Negative
Tumor Capsule: Not encapsulated
Lymph Vascular Invasion : Not present
Regional Lymph nodes: Not assessed
Distant Metastasis: Not assessed

Right side : Diffuse adenomatous hyperplasia

My surgeon will now refer me to an endocrine dr.

My question is - what does the pathology report mean in terms of further treatment - if any ? What follow ups are usually done for this type of cancer ?

What should I interpret , if anything, about the variant ? Is there something I should be discussing with the new doctor because it is this variant ?

I have never seen a dr about my thyroid prior to this and am not on any sort of replacement hormones yet. How long do I have before this would start to be a concern bearing in mind I dont even have a follow up referal yet ?

Is there anything else about this type of cancer you would think it useful to know.

Thank you
doctor
Answered by Dr. Binu Parameswaran Pillai (6 hours later)
Brief Answer:
NOT TO WORRY

Detailed Answer:
Hello,
Goodday.
First of all let me tell you that papillary carcinoma of thyroid is a slow growing tumour and can be well treated or cured. Please dont panic. It is not a bad cancer.

What you had was a micropapillary papillary thyroid cancer, which is unifocal and the type is oncocytic variety. This means that, you had a tumour which is less than one cm in size, which is confined to a single site ( unifocal) ( where as multifocal means more than one site). This tumour was small and didn't involve the capsule or vessel. This means that tumour spread outside the current site is unlikely. Oncoytic variant is not an aggressive type compared to many other varients of papillary cancer ( the other types are tall cell, classic varient etc).

Regarding further follow up.
1) you had total thyroidectomy. Now we need to assess the remaining areas in your neck and if the tumour is completely removed or not. We do a nulear scan approximately 6 weeks after the surgery to find out if there is any trace of thyroid tissue left in neck and if there is a remote possibility of tumour spread to a lymphnode. We also need to do a blood tests for TSH, Free T4, Thyroglobulin, Anti Thyroglobulin antibody. Your further course of action is based on this.

Based on the finding in nuclear scan, your endocrinologist will decide what to do next. He may opt for just treat you with Levothyroxine or give you radio iodine ablation, which is just taking a radio iodine tab/liquid by mouth. This is not at all painfull or complicated.

Your doctor may also opt to do an ultrasound of neck as well. These decisions are based on many factors and is best left to the treating doctor.

2) Now that you had total thyroidectomy, you need yto be started on Levothyroxine replacement for rest of your life. This is again a small tablet in morning which is a completely safe tablet. We ususally give a higher dose than normal in thyroid cancer to keep your TSH suppressed. This is to reduce the chance of regrowth of thyroid tissue. In your case, since the tumour was so small, this high dose may not be required, but again, the decision is best left to your endocrinologist. These are grey areas and each doctor has his policy based on local guidelines.

Further follow up is based on the initial treatment. However it is mainly a blood test after 6 months of initial treatment foloowed by an ultrasound or nuclear scan. If i discuss further, you will get confused. BE assured that, it is not an aggressive cancer and is easiy treable and possibly cured. Find out a good endocrinologist with experience in treating thyroid cancer and discuss with him. I am sure that he will guide you well.

Wish you all the best. If you need further clarifications, please feel free too ask

Kind Regards
Binu

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Binu Parameswaran Pillai (7 hours later)
Thank you for such an excellent comprehensive answer . I now know what to say and ask for.
doctor
Answered by Dr. Binu Parameswaran Pillai (18 minutes later)
Brief Answer:
Good luck

Detailed Answer:
Thank you and wish you good health
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Binu Parameswaran Pillai

Endocrinologist

Practicing since :2003

Answered : 1439 Questions

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What Does Papillary Carcinoma Of Thyroid Report Indicate?

Brief Answer: NOT TO WORRY Detailed Answer: Hello, Goodday. First of all let me tell you that papillary carcinoma of thyroid is a slow growing tumour and can be well treated or cured. Please dont panic. It is not a bad cancer. What you had was a micropapillary papillary thyroid cancer, which is unifocal and the type is oncocytic variety. This means that, you had a tumour which is less than one cm in size, which is confined to a single site ( unifocal) ( where as multifocal means more than one site). This tumour was small and didn't involve the capsule or vessel. This means that tumour spread outside the current site is unlikely. Oncoytic variant is not an aggressive type compared to many other varients of papillary cancer ( the other types are tall cell, classic varient etc). Regarding further follow up. 1) you had total thyroidectomy. Now we need to assess the remaining areas in your neck and if the tumour is completely removed or not. We do a nulear scan approximately 6 weeks after the surgery to find out if there is any trace of thyroid tissue left in neck and if there is a remote possibility of tumour spread to a lymphnode. We also need to do a blood tests for TSH, Free T4, Thyroglobulin, Anti Thyroglobulin antibody. Your further course of action is based on this. Based on the finding in nuclear scan, your endocrinologist will decide what to do next. He may opt for just treat you with Levothyroxine or give you radio iodine ablation, which is just taking a radio iodine tab/liquid by mouth. This is not at all painfull or complicated. Your doctor may also opt to do an ultrasound of neck as well. These decisions are based on many factors and is best left to the treating doctor. 2) Now that you had total thyroidectomy, you need yto be started on Levothyroxine replacement for rest of your life. This is again a small tablet in morning which is a completely safe tablet. We ususally give a higher dose than normal in thyroid cancer to keep your TSH suppressed. This is to reduce the chance of regrowth of thyroid tissue. In your case, since the tumour was so small, this high dose may not be required, but again, the decision is best left to your endocrinologist. These are grey areas and each doctor has his policy based on local guidelines. Further follow up is based on the initial treatment. However it is mainly a blood test after 6 months of initial treatment foloowed by an ultrasound or nuclear scan. If i discuss further, you will get confused. BE assured that, it is not an aggressive cancer and is easiy treable and possibly cured. Find out a good endocrinologist with experience in treating thyroid cancer and discuss with him. I am sure that he will guide you well. Wish you all the best. If you need further clarifications, please feel free too ask Kind Regards Binu