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What Causes Stomach Pain, Weight Gain And Pancreatitis After A Depo-Provera Shot?

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Posted on Mon, 16 May 2016
Question: My daughter took the Depo-Provera shot about 1 1/2 years ago. She had many of the side effects listed online including stomach pain, weight gain, strain throbbing in her stomach area, etc. She only took one dose and wished she would have read more of the side effects before taking the shot. Since then she has been diagnosed with pancreatitis twice. Both times doctors are telling her it has to be alcohol related because they ruled out cysts, gallbladder, etc. She is a college student and does go out on weekends with friends, but she is not an excessive drinker and drinks less than many her age. I truly believe that the Depo-Provera shot has caused some permanent damage to her stomach and/or pancreas. Has anyone had a doctor confirm that this could be the problem?
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Answered by Dr. Shoaib Khan (1 hour later)
Brief Answer:
Unfortunately no such instances reported, did a little research as well

Detailed Answer:
Hello ma'am/sir and welcome.

Thank you for writing to us.

I have gone through your query with diligence and would like you to know that I am here to help. I am really sorry to hear about your daughter, but from my experience I have never heard of any such serious implications (never anything permanent) caused by Depo-Provera. But just to make sure, I did do a little research only from trusted medical sites just to see if there were any such reported cases, and unfortunately there were no reported instances from any part of the world.

The only gastrointestinal implications from Depo-Provera shots were nausea, abdominal bloating, anorexia and abdominal pain. There were no other reported instances other than this.

But if you do not mind me putting forward a few possibilities, please do forgive me if I say something out of turn:

+In most cases with young adults, we can never be sure as to how much drug or alcohol consumption has taken place simply because the young adults do not want a judgemental intervention to take place, and most times also because they wouldn't want their parents or elders to find out. I am not saying that this is the case with your daughter, but it is possible that she has consumed more than you know.

+May be there were some pre-existing conditions that were aggravated by the use of Depo-Provera

+If she was any other medications, may be there was an interaction with some other medication or drug she consumed

I hope I did not say anything wrong to hurt your sentiments, I only say this out of concern for your child. Please do not hesitate to write back to me for any further clarifications, I would be more than happy to help.

Best wishes.
Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shoaib Khan

General & Family Physician

Practicing since :2009

Answered : 9409 Questions

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What Causes Stomach Pain, Weight Gain And Pancreatitis After A Depo-Provera Shot?

Brief Answer: Unfortunately no such instances reported, did a little research as well Detailed Answer: Hello ma'am/sir and welcome. Thank you for writing to us. I have gone through your query with diligence and would like you to know that I am here to help. I am really sorry to hear about your daughter, but from my experience I have never heard of any such serious implications (never anything permanent) caused by Depo-Provera. But just to make sure, I did do a little research only from trusted medical sites just to see if there were any such reported cases, and unfortunately there were no reported instances from any part of the world. The only gastrointestinal implications from Depo-Provera shots were nausea, abdominal bloating, anorexia and abdominal pain. There were no other reported instances other than this. But if you do not mind me putting forward a few possibilities, please do forgive me if I say something out of turn: +In most cases with young adults, we can never be sure as to how much drug or alcohol consumption has taken place simply because the young adults do not want a judgemental intervention to take place, and most times also because they wouldn't want their parents or elders to find out. I am not saying that this is the case with your daughter, but it is possible that she has consumed more than you know. +May be there were some pre-existing conditions that were aggravated by the use of Depo-Provera +If she was any other medications, may be there was an interaction with some other medication or drug she consumed I hope I did not say anything wrong to hurt your sentiments, I only say this out of concern for your child. Please do not hesitate to write back to me for any further clarifications, I would be more than happy to help. Best wishes.