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What causes elevated GGT level in blood?

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Posted on Wed, 20 May 2015
Question: GGT 665
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Answered by Dr. Mohammed Taher Ali (24 minutes later)
Brief Answer:
Elevated GGT suggestive of liver disease.

Detailed Answer:
Dear Sir, Hi

Thanks for posting your query on HCM.
I appreciate your concern for the blood test report showing a very high,

Incomplete data: Medications history, alcohol intake??? any existing disease, duration of elevated GGT...not mentioned.

The gamma-glutamyl transferase (GGT) is primarily present in Liver, Kidney, and pancreatic cells.

Normal Reference Values for age 41-45 years: 9-37 U/L

The given result is 20 times normal.

It is an index of liver cell injury caused by toxins such as alcohol, drugs, poisons, etc.

Such high levels are usually due to liver diseases, such as hepatitis like alcoholic liver disease or cirrhosis and gall bladder diseases.
Even small amounts of alcohol within 24 hours of a GGT test may cause a temporary increase in the GGT.
Other conditions, such as congestive heart failure, diabetes, or pancreatitis may also increase the level of GGT.
Drugs like Phenytoin, Carbamazepine, and Phenobarbital are also known to increase the level.

Hope this answers your query.
Should you need more clarification, please feel free to send your query.

Wishing you a very good health.

Above answer was peer-reviewed by : Dr. Raju A.T
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Answered by
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Dr. Mohammed Taher Ali

General & Family Physician

Practicing since :1988

Answered : 6133 Questions

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What causes elevated GGT level in blood?

Brief Answer: Elevated GGT suggestive of liver disease. Detailed Answer: Dear Sir, Hi Thanks for posting your query on HCM. I appreciate your concern for the blood test report showing a very high, Incomplete data: Medications history, alcohol intake??? any existing disease, duration of elevated GGT...not mentioned. The gamma-glutamyl transferase (GGT) is primarily present in Liver, Kidney, and pancreatic cells. Normal Reference Values for age 41-45 years: 9-37 U/L The given result is 20 times normal. It is an index of liver cell injury caused by toxins such as alcohol, drugs, poisons, etc. Such high levels are usually due to liver diseases, such as hepatitis like alcoholic liver disease or cirrhosis and gall bladder diseases. Even small amounts of alcohol within 24 hours of a GGT test may cause a temporary increase in the GGT. Other conditions, such as congestive heart failure, diabetes, or pancreatitis may also increase the level of GGT. Drugs like Phenytoin, Carbamazepine, and Phenobarbital are also known to increase the level. Hope this answers your query. Should you need more clarification, please feel free to send your query. Wishing you a very good health.