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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is pneumococcal vaccine safe for G6PD with seizure disorder?

My 5-year -old son is G6PD Deficient. He also has seizure disorder (on phenobarbital, currently at 45mg in the morning and at bedtime). Pneumococcal vaccine is recommended by his pediatrician. Is this safe for G6PD with seizure disorder? Please advise. Thanks!
Thu, 25 Feb 2021
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General & Family Physician 's  Response
Hi,

According to the recent studies, G6PD deficiency increases risk of pneumococcal bacteremia in areas under high malaria transmission. So, if your child is G6PD deficient then prevention of infection is important. This is no scientific evidence that vaccines are a medication that will trigger an episode. Therefore, immunizations like pneumococcal vaccine are not contraindicated in people with G6PD deficiency.

Again, according to the CDC, there may be a small increase risk in the of febrile seizure when PCV13 or pneumococcal vaccine is given by itself. But, there is no risk found in case of other type of seizures except febrile seizure when pneumococcal vaccine is administered. At most 30 febrile seizures in 100,000 children vaccinated by pneumococcal vaccine were found. For that reason, CDC continues to encourage the vaccine of children according to the vaccination schedule, which allows for the pneumococcal vaccine to be given during its schedule time.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Zubayer Alam, General And Family Physician
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Is pneumococcal vaccine safe for G6PD with seizure disorder?

Hi, According to the recent studies, G6PD deficiency increases risk of pneumococcal bacteremia in areas under high malaria transmission. So, if your child is G6PD deficient then prevention of infection is important. This is no scientific evidence that vaccines are a medication that will trigger an episode. Therefore, immunizations like pneumococcal vaccine are not contraindicated in people with G6PD deficiency. Again, according to the CDC, there may be a small increase risk in the of febrile seizure when PCV13 or pneumococcal vaccine is given by itself. But, there is no risk found in case of other type of seizures except febrile seizure when pneumococcal vaccine is administered. At most 30 febrile seizures in 100,000 children vaccinated by pneumococcal vaccine were found. For that reason, CDC continues to encourage the vaccine of children according to the vaccination schedule, which allows for the pneumococcal vaccine to be given during its schedule time. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Zubayer Alam, General And Family Physician