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What are the side effects of methotrexate on bladder and vagina?

Mar 2016
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Practicing since : 2011
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What are the side effects of methotrexate related to the badder and the vagina?
Posted Mon, 2 Sep 2013 in Women's Health
Answered by Dr. S Patra 1 hour later
Brief Answer:
Methotrexate has several side effects.

Detailed Answer:

Thanks for writing to us.

Side effects occur due to high dose of Methotrexate. The following ones are related to bladder and vagina:

1) Bladder inflammation and cancer (in long term use).
2) Renal impairment and hematuria (bloody urine).
3) Vaginal pruritus (itching) and infection.
4) Vaginal bleeding or spotting.

Folinic acid supplement is given as antidote of Methotrexate toxicity. If the patient suffer from any of these symptoms, it is worthwhile to consult the treating doctor and ask for folinic acid supplement.

Hope, above information is quite helpful. Let me know, if you need any clarification.

Wish your good health. Good luck.

Dr Soumen
Above answer was peer-reviewed by
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